unit 9 pt 5 Flashcards
pathogenesis of WNV
ciruclates between birds and mosquitos where birds amplify and develop higher viral loads
–> humans are dead-end hosts
passed through vectors
clinical manifestations of west nile virus
most people are asymptomatic while 20% experience flu symptoms
–> 1% can develop neuroinvasive disease (encephalitis and meningitis)
risk factors for severe disease WNV
old age, immunocompromised
theories on how WNV reached the US
algorithm for diagnosis of WNV infection
perform serology to detect WNV IgM
–> presence of IgM must be confirmed because cross reactivity can cause false positives
control methods for preventing WNV infections
avoid mosquitos and control their population
pathogenesis of zika virus
most infections are asymptomatic and will resolve itself; risk of congenital infections that cause microcephaly
pathogenesis of ebola virus
causes infection and activation of all immune cells (entire immune system)
–> experience dry symptoms then wet symptoms and if severely effected then you will suffer from organ failure
morphology of ebola virus under electron microscope
long worm like virus
reservoir and route of infection used by hantavirus
transmission from rodents
what is the hantavirus most often detected in the US
Sin nombre virus in which deer mouse are the reservoir
clinical manifestations of the hantaviruses
HPS: nonspecific symptoms then shortness of breath and pulmonary edema
HFRS: nonspecific then hypotension and acute kidney failure
pathogenesis of sars-Cov
transmitted through contact with palm civets
–> typically experience nonspecific cold like symptoms which can develop into pneumonia in the LRT
pathogenesis of mers-cov
transmitted through contact with camels
–> typically experience URT symptoms which can develop into severe disease with organ failure and septic shock
pathogenesis of sars-cov-2
nonspecific symptoms
