unit 2 definitions

Question 1

immunogen

Answer 1

substance CAPABLE of inducing immune response (stimulates)
–>CREATES immune response

Question 2

antigen

Answer 2

substance that interacts with B cell receptor, T cell receptor, or antibody

Question 3

hapten

Answer 3

molecule too small to be immunogenic so it attaches carrier molecule (which allows it)

Question 4

epitope

Answer 4

antigenic determinant or binding site on antigen

Question 5

agretope

Question 6

valence

Answer 6

number of epitopes an antigen carries

Question 7

antigenicity

Answer 7

total capacity of antigen to bind to antibody (DOES NOT MEAN IMMUNOGENICITY BECAUSE Ag-Ab BINDING DOES NOT ALWAYS RESULT IN IMMUNE RESPONSE)

Question 8

immunogenicity

Answer 8

ability or capacity to stimulate immune response

Question 9

heterophile antigens

Answer 9

similar antigens in structure, but from a different species

Question 10

antibody

Answer 10

immunoglobulins produced in response to antigens

Question 11

allotype

Answer 11

multiple alleles for the same antibody

Question 12

idiotype

Answer 12

unique amino acid sequence of heavy and light chain domains

Question 13

isotype

Answer 13

classes of antibody (IgG, IgM, IgD, IgA, IgE)

Question 14

hybridoma

Answer 14

hybrid cell that combines B cells and myeloma cells