Unit 5 Lecture Flashcards
Define cellular respiration
A series of chemical reactions where the respiratory system allow oxygen into the blood to the delivered to body cells for ATP production
Define inspiration
Describe the movement of air into the lungs
Define expiration
Movement of air out of the lungs
What muscle are embedded between the ribs and help humans breathe very deeply in and out above the normal breathing
Intercostal
In the pulmonary circuit , arteries and arterioles carry what ? Blood
Deoxygenated blood
In the pulmonary circuit venues and veins what blood?
Oxygenated blood
As you breath in through your mouth and or nose air pass through what passage way? Food and liquid also pass through this area
Pharynx
This airway is the most superior part of the lower respiratory tract
Trachea
To ent either the left or right lung air flow must flow through the left or right what ?
Bronchus
What are these? They are small collapsible passageways that are surround by smooth muscle cells. They are transition zone between the main airways and the exchange epithelium of the lungs
Bronchioles
These terminal air safe in the lungs are where oxygen can enter the pulmonary circulation and carbon difusor can leave
Alveoli
What is the main muscle that controls the rate and depth of breathing ? It forms the floor of the thoracic cavity
Diaphragm
There are 2 main types of cells that make up the walls of the terminal sacs in the respiratory system. What type synthesis a chemical surfactant and secrete it to mix with fluid in those air sacks. This mixture makes it easier for these air sacs to expand during breathing
Type 2 pneumocytes
There are two main type of cells that make up the walls of the terminal sacs in the respiratory system. These cells make up the walls of the terminal sacs called ? They are very thin so that gases can diffuse rapidly through them in or out of blood
Type 1 pneumocytes
What kind of gradient does gas, liquid always move down? From high to low?
Pressure gradient
What is Dalton’s law?
Air is a mix of gases, nitrogen, oxygen carbon dixiode as well little water. This gas law is The total pressure exerted by a mixture of those different gases
What does partial pressure refer to?
When physiologist refer to pressure a single gas in mixture we put a “P” in front of the gas abbreviated. The “P” stands for partial pressure
Define Boyles law
The inverse relationship of the thoracic cavity and inside pressure.
As volume in thoracic cavity increased the lungs decrease, the pressure inside will decrease.
Define tidal volume
When looking at an X and Y graph. If you breath quietly, the volume of air that moves during a single inspiration or expiration
After someone takes a normal restful breath there is still a lot of lung volume yet to be used. The lung volume above restful breathing is tapped into during exercises is known as what?
Inspiratory reserve volume
A lung capacity is the sum of two or more lung volumes. The sum of the volumes tidal volume and inspiiratory reserve volume is known as
Inspiratory capacity
Define expiratory reserve volume
If someone does a restful exhale and then forcibly push
What is the volume of air that cannot be exhaled because the larynx, trachea and bronchi can’t completely close?
Residual volume
Define hypoxia
A lack of ATP that’s made from lack of oxygen means there is not enough energy available to maintain homeostasis and cells start to die
Define hypercapnia
Levels of carbon dioxide are above normal
hyper: above
Capnia : carbon dixiode
When oxygenated blood reached a systemic capillary bed, oxygen will diffuse out rid the blood and into body cells, since those body cells contain a Po2 that is (less than or greater than ) the Po2 in oxygenated blood
Less than
At systemic capillaries body cells are producing carbon dioxide through normal cellular respiration. Causing co2 to diffuse into the blood, since it’s levels in these body cells would be (less than or greater than?) the pco2 in blood
Greater than
Since deoxygenated blood has greater Pco2 than oxygenated blood it is slightly (more acidic or more alkaline) than oxygenated blood
More acidic
Each hemoglobin molecules contains four what? They bind to oxygen and contain one iron ion on each
Heme groups
Define cooperative binding
Hemoglobin bind each oxygen molecule progressively increased it affinity for more oxygen
What is carbonic anhydrase
An enzyme that converts co2 and h20 into H+ ions and hco3- .
What substances can allostericslly inhibit hemoglobin?
CO2 & H+
Since area of the body are metabolically active will they be more acidic or more alkaline than place in the body less active. Why?
More acidic , due to the abundance of H+ ions in those living tissues
What kind of relationship is there between metabolic activity and the amount of O2 that hemoblogin drops off at those tissues?
Direct relationship
What are the three places for gas exchange?
Ventilation
External respiration
Internal respiration
Define ventilation
Also known as breathing but the • atmosphere and alveoli
Define external respiration
Between the blood and alveoli
•Alveoli to pulmonary capillaries
Define internal respiration
Between the blood and tissues
•Systemic capillaries to body tissues
How is gas influenced by resistance?
The diameter of the smooth muscle on bronchioles (airway tubes) change diameter and modulate air flow.
What kind of nervous control are the bronchioles under?
Autonomic and local
What anatomy is the conducting zone for the respiratory system?
Nadal cavity, trachea
Where is the upper respiratory tract for the respiratory system
Nadal cavity, tongue, larynx, esophagus and pharynx
Where is the lower tract of the respiratory tract?
Trachea, right & left bronchus, diaphragm and lungs
Of the alveolar cells which type cause gas exchange?
Type 1 alveolar cells
Of the alveolar cells which type secrete surfactant?
Type 2
What is tidal volume
Also known as restful breathing
What law describes the total pressure as a mixture of gases is the sum of the partial pressures (P) of all individual gases
Daltons laws
Which law describes the inverse relationship between pressure & volume of a sealed chamber?
Increased volume decreases pressure.
Increased pressure means decreased volume
Boyles law
What increased during inspiration?
Thoracic volume increases
What decreases and increases during expiration?
Dia
What are two factors affecting lung tissue?
Compliance and elasticity
Define compliance
The ability to stretch
Define elasticity
The ability of lung tissues to return to it’s resting volume when stretching force is released
What are features of healthy lungs?
High elasticity and high compliance
What is carbonic acid equation
H2 co3
What is the bicarbonate equation
HCO3-
What factors affect air flow resistance?
Length of the system
Viscosity of air
Diameter of air way
What are the levels of o2 & co2 for hyperventilation
⬆️ Po2
⬇️ Pco2
What are the levels of o2 & co2 for hypoventilation?
⬆️ Pco2
⬇️ O2
Define ventilation perfusion coupling
control of bronchiole & arteriole diameter to sustain pulmonary perfusion to the same quality of alveolar ventilation
Respiratory alkalosis
Increased pH during hyperventilation
What is respiratory acidosis
When pH is too low comes from hypoventilation
If co2 levels are increased? How do the bronchioles, pulmonary arteriole , arteriole and pre-capillary sphincter respond?
Bronchiole: dilate
Pulmonary arteriole :Constrict
Arteriole and pre-capillary sphincter :dilated
If Pco2 levels are decreased ? How do the bronchioles, pulmonary arteriole , arteriole and pre-capillary sphincter respond?
Bronchiole : constrict
Pulmonary arteriole : dilate
Systemic arteriole and pre-capillary sphincter : constrict
What factors affect the diffusion of co2 & o2
Temperature , solubility and pressure gradient
How does solubility of co2 & o2 differ?
How does temperature affect gas diffusion
⬆️ temp = ⬆️ gas diffusion rate
What are ideal levels of deoxygenated blood for co2& o2 & pH
Po2 ≤ 40mmhg
Pco2 ≥ 46 Maggie
pH: 7.37
What are ideal levels of oxygenated blood for co2& o2 & pH
Po2 =100 mmhg
Pco2= 40 mmhg
pH : 7.4 pH
Define oxyhemoglobin
To gain oxygen
Does co2 & o2 aqueous dissolve well?
No, they need assistance and get it from hemoglobin . However co2 is more soluble than water but both awful at doing so
Story time : oxygen
- Oxygen
- Is dissolved in plasma
- Hemoglobin in RBC bind to oxygen
4.Hb transport from pulmonary system to systemic system - Cells have a low pressure gradient for o2 so Hb released o2 to enter the cells
- O2 dissolved in plasma
- Cells use the o2 for cellular respiration
How many oxygen molecules can bind to one Hb?
4
Define cooperative binding
When Hb exhibits a binding one o2 molecule increased affinity for another o2 molecule
What factors affect Hb-o2 bonding
PCO2
pH
Temperature
2,3 BPG
If there is high, medium and low levels of co2 how does this affect hemoglobin saturation from oxygen
⬇️ co2: ⬆️ Hb saturation
Med :
⬆️ co2 : ⬇️ Hb saturation
If there is high, medium and low levels of pH how does this affect hemoglobin saturation for oxygen
⬆️ pH : ⬆️ Hb saturation
Mid : mid
⬇️ pH : ⬇️ Hb saturation
If there is high, medium and low levels of temperature how does this affect hemoglobin saturation for oxygen
Colder : ⬆️ Hb saturation
3.7 ° c Mid : mid
Hot : ⬇️ Hb saturation
What structure is the temporary holding place for urine
Bladder
What is the anatomy structure that urine passes through after it has been filtered out of the blood
Ureter
What is bean shaped organ that filters waste out of blood.
Kidney
What organ regulates blood pressure,
Kidney
What organ erythrocytes production
Kidney
What organ balances blood pH and blood solute levels
Kidneys
Dirty blood flows into this filtering organ called?
Renal artery