Unit 4 Lab Flashcards
Define metabolism
Chemical process that occur within a living organism in order to maintain life
Define incidence
The frequency of a disease in a specified population over a period of time
Define absorption
transfer of substance from the GI tract to extracellular space
Define digestion
The process of mechanically and enzymatically breaking down food into substances for absorption into the blood stream
Define metabolism
chemical reactions throughout the body
Define hyperglycemia
Excess glucose in blood stream often associated with diabetes mellitus
Define anabolism
metabolic pathway in which energy is needed in order to synthesis small molecules into bigger ones
Define diabetes mellitus
Disease where insulin production is impaired resulting in abnormal high blood glucose levels
Hypoglycemia
Lack of glucose in blood stream
What type of signal molecule is secreted from the endocrine cell in the blood?
Hormone
What to target cells have that will receive the signal molecule to bind
Receptors
What chemical class is epinephrine
Amino acid
Growth hormone is produced where
Anterior pituitary gland
What is the process to breakdown stored carbohydrates into it monomer form
Glycogenolysis
What is the process name of breaking down stored fat into its monomer
Lipolysis
What energy pathway does (glucose) enter?
Glycolysis
What is the final product of glycolysis?
Pyruvate (2 of them)
What happens to pyruvate under aerobic conditions
Enter the mitochondria & converted to triglycerides
What is the process of breaking down fatty acids into acetyl CoA
Beta oxidation
What are normal values for glucose test
Glucose should never exceed 200 mg/dL
What are the blood glucose levels for hyperglycemia individuals
100-125 mg/dL
What test is used to identify glucose levels
Hemoglobin A1C test
Define glycated , why is it bad
When glucose attachments to proteins that changes their structure and function negatively. This may cause a autoimmune reaction
What are blood glucose levels for hypoglycemia?
Below 70mg /dL
What are the 3 basic types of chemical classes of hormones?
Amino acids, peptides and steroids
Which of the 3 basic types of chemical class of hormone are polar?
Peptide
Which of the three basic chemical class add non-polar?
Steroids
Where must peptide hormone receptors be located for target cells?
On plasma cell membrane of cells
Where must steroid hormone receptors be located for target cells?
Inside the cell
Feed back loop for ⬆️ glucose level
• ⬆️ blood glucose
• pancreatic B-cells
• pancreatic B-cells
• ⬆️ insulin released into blood
• hepatocytes w/ insulin receptors
1. ⬇️ glucose concentrations inside hepatocytes
2. ⬆️ glucose transport into hepatocytes via glut 2 transporters
3. Glucose is converted into glycogen for storage
4. ⬆️ glycogenesis
• ⬇️ blood glucose levels
Feed back loop for ⬇️ glucose levels
• ⬇️ blood glucose level
• pancreatic Alpha cells
• pancreatic alpha cells
• ⬆️ release of glucagon into blood
• hepatocytes into blood w/glucagon receptors
1. ⬆️ glycogenolysis
2. ⬆️ glucose concentrations inside hepatocytes
3. ⬆️ released glucose to blood through GLUT2 transporter
• ⬆️ blood glucose
How much of the population make up type 2 diabetes? Type 1?
Type 1: 10%
Type 2: 90%
How is type 2 diabetes treated
Through exercise (associated with better glut -4 transporter) and dietary changes (eat food with low glycemic index)
What are the transporter responsible for glucose from blood to the liver cells?
GLUT - 2 transporter
What are the transport responsible for transporting glucose from blood to the muscle and fat vells?
GLUT - 4 transporters
Fatty acids must be converted into acetyl CoA which pathway does this molecule enter?
Kreb cycleor citric acid cycle