Unit 3 Lab Flashcards
Define cardiac cycle
The performance of the heart from beginning to end of a heart beat
Define heart rate
A minute of how many times your heart beats
Define systole
The contraction phase of the heart
Define diastole
Ventricle filling, relaxed
Define stroke volume
Amount of blood from the left ventricle
Define cardiac output
Quantity of blood pumped by the heart in a given time
Define systemic circulation
Oxygenated blood circulate the body
Define pulmonary circulation
Gathering deoxygenated blood to be sent to the lungs to become oxygenated
Define peripheral resistance
Resistance from blood vessels
What are the five kororoff phases
What are the target cells for altering heart rate? (Location and type of myocardial cells )
SA Node
Conducting cells
What is the neurotransmitter released at the target cell of the sympathetic system
Norepinephrine
Which specific receptors are found in the heart by Norepinephrine ?
Beta 1
What is the neurotransmitter released at a target cell of the parasympathetic branch
Acetylcholine
Which specific receptors are found in the heart for this neurotransmitter?
Muscarinic
What are the target cells for altering stroke volume (location and type of myocardial cells
Left ventricle
Contracting cell
What type of adrenergic receptor is is found on arterioles that stimulate smooth muscle contraction and vessel contraction
Alpha 1
Which signal molecules bind to alpha 1 andrenergic receptor
Norepinephrine
What signal molecule bind to alpha 1
Norepinephrine
What type of signal molecule is norepinephrine
Monoamine
What type of adrenergic receptor is found on arterioles that stimulate smooth muscle relaxation and dilation
Beta 2
Which signal molecules bind to beta 2
Epinephrine
What type of signal molecules is epinephrine? Where does it come from
Monoamine Neurohormone from adrenal medulla
What is the primary integrating center for regulation of the cardiovascular system
Medulla oblongata
What are they called? Proteins or glycoprotein on the surface of a cell which can innitate an immune response
Antigen
What is the technical term for antibody?
Immunoglobulin
What is a allele
On of two or more possible forms of a gene coding for a specific characteristic
What is agglutination ?
If the wrong blood is transfused into a person the blood cells will clump
What is turbulent flow?
The first pulse sound that defines the systolic BP
Define laminar flow
When blood is basically flowing without disturbance and determines the diastolic pressure
What unit is blood pressure measured?
Millimeters of mercury
What units is heart rate measured in?
Beats Per Minute
What is the name of the cardiac cycle during contraction
Systole
What’s the name of the cardiac cycle when it’s relaxed, and refilling
Diastole
Define heart rate
The number of cardiac cycles per minute
Define hypertension
Excessively high blood pressure
What is a stethoscope
A tool used to listen into blood pressure for specific sounds of the heart
What does systolic mean
The high pressure measured during blood pressure monitoring
What is a sphygomomanometer
Instrument used to create pressure of bloood in the blood vessels
What is a korotkoff sound
The name of sounds heard while measuring blood pressure
Define agglutination
Blood cells clump if wrong blood type is administered to a person
To test negative or positive for something means that the specific trait or condition is absent
Negative
To test positive or negative for something means that a specific character trait or condition is present
Positive
What is the technical term for antibody
Immunoglobulin
Define antigen
Proteins or glycoproteins on the surface of a cell that stimulate a immune response
Define antigen
Proteins coded by your DNA , on cells as an ID tag
Define Antibody
“YShape proteins involved ⬆️ an immune response , produced by B lymphocytes
Define agglutination
Clumping of cells when antibodies attach to them
Define allele
One of two or more versions of a gene. Genes can be dominant or recessive
Define genotype
A description of the alleles inherited from parents
Define albumins
simple form of protein that is soluble in water contribute to plasma colloid osmotic pressure ( keeping fluid in a vascular space )
Define phenotype
Physical characteristics that results from a particular genotype
Define globulins
Clotting factors, enzymes , antibodies , carries for various substances
Define a lymphocyte
They produce specific immune responses directed against invaders
Define a monocyte
They are phagocytes that develop into macrophages and migrate into tissue
Define neutrophils
What antigen does type A blood have?
B ?
AB ?
O?
Blood A has A antigen
Blood B has B antigen
Blood AB has A+ B antigens
Type O has neither A or B antigens
Which blood types of dominant? Recessive?
A= B : dominat
O: recessive
In which component of blood are antibodies located in? Plasma or formed elements?
Plasma
What antigens does type A have?
B?
AB?
O?
A has B antigens
Define rhesus
Another important factor on erythrocytes that can elicit an immune response
Which Rhesus factor is dominant?
+ is dominant
- is recessive
Which blood type is the universal donor?
O type , it would not introduce set off any immune response
Which blood type is universal recipient
AB type, it has no antibodies to cause agglutination. No antigen are going to be foreign
What are the consequences of innorrect blood typing?
steps?
First : agglutination
Second : ischemia blood flow to tissues
Third : hypoxia occurs In all over the body
Fourth: necrosis occurs due to insufficient ATP to maintain homeostasis
If a father has a positive Rhesus and mother with negative Rhesus what will happen?
First pregnancy the mom won’t produce anti Rh antibodies until after giving birth the first time.
Everytime after the mom produced anti Rh antibodies . Therefore the second Rh+ fetus seen as foreign
What componentes are in formed elements
Erythrocytes, leukocytes& thrombocytes
Where are proteins and glucose found in blood?
Plasma
What subcategory do antibodies fall into for plasma proteins?
Globulins
Blood type is based on the presence of antigen on the cells
Red blood cells
When antibodies bind to antigens on red blood cells the cell will clump together. What is this called?
Agglutination
Someone with type A blood has these antibodies
Anti B antibodies
If tested for the Rh factor the blood cells will clump only if the blood is Rh ? Positives ? Negative?
Positive
The Rhfsxtor may only concern if the mother is Rh ? Negative? Positive?
Negative
What are the possible genotypes for someone with type B blood
(B,B) (O,B)
What is the name of the hormone that stimulates Red blood Blod Cell production?
Erythropoietin
Having low hemoglobin or red blood cell count is called?
Anemia
What is the functional unit of a kidney?
Nephron
What is the fluid that leaves the blood then moves through the functional unit of the kidney
Filtrate
Kidney affect what one major factor that affects blood pressure?
Total blood volume
What the proceeds of fluid and substances moving out of the glomerular capillaries and into the tubule
Filtration
What is the process of substances being taken from the nephron tubule and returned to the blood ?
Reabsorption
Urine is simply fluid removed from what major component of blood?
Plasma
What sensors are de ring when someone is dehydrated or overhydrated?
Osmoreceptors
Define excretion
Elimination of materials from the body (urinating)
Define micturition
Technical term for urinating
What are the organic molecules that get filtered out of the blood and become part of the filtrate?
Glucose, C02, amino acids, vitamins, nitrogenous waste, small proteins , Hco3- , lipids
What category of molecules in the plasma is prevented from passing through the glomerular filter
Plasma proteins
What are the functions of the urinalysis system?
- Water & electrolyte balance
- waste removal
- Ph regulation
- Red blood cell production
What is osmolatity ratio?
Miliosmoles / 1 L of H20
Which major component of blood (plasma vs formed elements / cellular components ) contains substances that are completely prevented from passing through the glomerular filter
Formed , cellular elements
Whats the normal range of mOsm
290-300
How much filtrate does the kidney produce?
180 L of filtrate
How many L is secreted from the body of the kidney a day?
1-2 Liters
Define obligatory Water Loss
The minimum volume that must be excreted to remove metabolic waste and maintain kidney function . On average 400 mL urine / day
What is normal pH in the body
7.35-7.45
Average is 7.4
Define osmotically active solute
Water moves across a membrane to a location with more solutes
What is the function of the kidneys?
Filter and process into filtrate of blood and urine
What is the bladder do?
Hold the urine until to find the bathroom
Function of the urethra?
Place where the urine exits
Function of the cortex in the kidney?
Destination where all filtering and most of the reabsorption occurs
Medullla function in the kidney?
High levels of solutes to ensure maximum water absorption
Nephrons function in kidney?
The functional unit of the kidney that is partially in the cortex and medulla. Their ducts collect urine into the renal pelvis
Renal pelvis function
Funnels urine into ureter
Uréter function in kidney?
Conducts urine to the bladder
Define filtration in the nephron
Random movement of water and small solutes. Nephron created clear -ish fluid in the nephron
What are the three major functions of the nephron?
Filtration , absorption, secretion
Define reabsoprtion
Returns solutes and water (good stuff) back into the blood from the filtrate as the body needs it
Where does filtration occur
Glomerulus capsule and bowman’s capsule to produce filtrate
Define secretion
The back up to the random filtration process.
It’s a selective removal of excess bad stuff through active transport into filtrate for disposal
Where is reabsorption occurring in the nephron?
Proximal tubule , loop of henle (ascending and descending) , distal tubule and collecting duct
Where does secretion occur in the nephron?
Proximal tubule , distal tubule & collecting duct
What does how much reabsoprtion takes place at the proximal tubule?
what substances are being absorbed?
65% of filtrate volume is reabsorbed here
Substance : water , ions organic molecules
What is reabsorbed in the descending limb of the loop of henle?
Water only
What is reabsorbed in the ascending limb?
Solutes only (ions) k , na , cl
What stimuli affect nephrons?
- total blood volume
- Blood osmolarity
- pH
Define proteinuria / albuminuria
Substance present in urine
Define hematuria
Red blood cells in the urine
Define glycosuria
Glucose is found in the blood
What are the hormones affecting kidney function
Vasopressin , aldosterone and atrial natiuretic hormone
What does vasopressin do in the kidney?
Increase water reabsorption
What does aldosterone do in the kidney function
Increase sodium reabsorption & increase potassium secretion
What does atrial natriuretic hormone do in the kidney?
Reduced water and salt reabsoprtion
Increased water excretion
What 4 specific substances should not be in urine because they should not pass through the filter
- Leukocytes
- Erythrocytes
- Small dissolved ions
- Proteins
What 5 specific substances should be reabsorbed in the nephron
- Ions
- Amino acids
- Water
- Small proteins
- Glucose
What are chemical classifications
Amino acids
Peptides
Steroids
What type of signal molecule is secreted from a endocrine cells into the blood
Hormone
What do target cells have what where they receive signal molecules will bind
Receptors
Epinephrine is this type of hormone (chemical class)
Amino acid
What organ produced the growth hormone
Pituitary gland
Hormones of this chemical class can have receptors inside the cell
Steroid
Hormone of this chemical class is produced by the adrenal cortex
Steroid
Insulin is what type of chemical class hormone?
Peptide
Reproductive hormones are part of what chemical class?
Steroid
What hormone is secreted by the heart ?
ANP ( Atrial Natriuetic peptide )
What hormone is produced by the pancreas has the opposite actions at target cells than insulin
Glucagon
What structure secrets vasopressin
Posterior pituitary gland
If water is being reabsorbed from the DESCENDING LIMB of the loop of henle what happens to the concentration from the top of the limb to the bottom
Concentration goes up
If ions are being reabsorbed from the ascending limb what happens to the concentration? From the filtrate from the bottom of the loop to the top
Concentration goes down
Which must move first - water from descending limb or ions from the ascending limb?
Ions , because it is osmotically active solute to draw in water
Define hematocrit
Ratio of erythrocytes to total blood volume