Unit 4- Chapter 13 Flashcards
Why do pathogens change antigens?
So new antibodies have to be made
Strep pneumonia changes:
How many different possible serotypes?
Polysaccharides on its capsule
90
In influenza, antibodies are made against-
Glycoproteins on the surface - Hemagglutinin (HA) and neuraminidase (NA)
Small mutations change surface proteins
Antigenic drift
Mutations with bigger changes, or reassortments, between two or more viruses
Antigenic shift
Step and influenza involve:
Improper memory against it because they change too much
What change their surface antigen by rearrangements of genes - happens when entering inside the body
Trypanosomes
What do Trypanosomes change?
Variable surface glycoproteins (VSG)
What does the trypanosomes cause the body to do
Reset its antibody production
What does Salmonella typhimurium change?
It’s flagellar protein
What does Neisseria gonorrhea change?
Pili proteins
Herpes virus enters into human cells and can become:
Latent (hides)
Where does the perpetrator virus hide?
In the neurons
Goes back to the neuron after it comes out, so cannot be removed
What happens with the herpes virus during latency?
No replication or production of viral peptides occurs- no disease
Neurons have few:
How is this beneficial for herpes?
MHC Class I
They can go undetected here and can just hang out until they are ready to come out