Unit 3.8

Question 1

Antifungal used for deep mycoses; rapid onset of activity; high incidence of nephrotoxicosis.

Answer 1

amphtericin B

Question 2

Antifungals used for deep mycoses; 5-10 days to become fungicidal; does not produce nephrotoxicosis.

Answer 2

azoles

Question 3

Antifungal used to treat superficial mycoses like ringworm; causes skeletal, skull and nervous system defects in kittens born to queens treated with this drug.

Answer 3

griseofulvin

Question 4

What antifungal comes in “microsized” and “ultramicrosized” needed for absorption.

Answer 4

griseofulvin

Question 5

What -azole antifungal is used only for topical application because it is not absorbed PO; has been used for Aspergillosis of the nasal cavity and to treat Malessezia yeast in the ear canal.

Answer 5

clotrimazole

Question 6

What are three commonly used anti-fungals for topical application?

Answer 6

clotrimazole, miconazole, nystatin

Question 7

What form of amphotericin B is less nephrotoxic?

Answer 7

liposomal forms