Unit 3.5

Question 1

This means a drug binds to some other compound (e.g. calcium, iron, etc.) and precipitates out of solution

Answer 1

chelated

Question 2

This term describes the phenomenon by which a drug causes the kidney to not reabsorb all the glucose from the urine resulting in glucosuria without hyperglycemia

Answer 2

Fanconi’s syndrome

Question 3

Which two of the tetracyclines are hydrophillic and more likely to be chelated by calcium than newer members of the family?

Answer 3

tetracycline, oxytetracycline

Question 4

Which two of the tetracyclines are more lipophillic and thus more indicated for CNS signs of rickettsial diseases like Lyme disease?

Answer 4

doxycycline and minocycline

Question 5

What drugs produce Fanconi’s syndrome?

Answer 5

expired tetracycline and oxytetracycline

Question 6

T or F

Time dependent antibiotics ideally need to be present at the infection site continuously.

Answer 6

True

Question 7

T or F

Drug residues from antimicrobials typically are NOT degraded by cooking or pasteurization.

Answer 7

True

Question 8

T or F

Tetracyclines cause bone damage in rapidly growing animals.

Answer 8

False

Question 9

What is the site of action for the following drug?

Penicillins

Answer 9

cell wall

Question 10

What is the site of action for the following drug?

Cephalosporins

Answer 10

cell wall

Question 11

What is the site of action for the following drug?

Aminoglycosides

Answer 11

ribosomal production

Question 12

What is the site of action for the following drug?

Quinolones

Answer 12

key enzyme

Question 13

What is the site of action for the following drug?

Tetracyclines

Answer 13

ribosomes/protein production

Question 14

Why should tetracycline or oxytetracycline not be given to young animals, if possible?

Answer 14

If administered during first few weeks of animal’s life, will combine with enamel while teeth are being developed.