Unit 1.2

Question 1

this is released by the hypothalamus to stimulate the pituitary gland to produce ACTH

Answer 1

corticotropin releasing factor

Question 2

release of ACTH results in what hormones being produced by what gland?

Answer 2

hydrocortisone & cortisone, adrenal gland

Question 3

this term means the glucocorticoids are administered as drugs

Answer 3

exogenous glucocorticoids

Question 4

a drug dissolved in water is called what type of dose form?

Answer 4

aqueous

Question 5

a drug mixed with, but not dissolved in, a liquid is referred to as what type of dose form?

Answer 5

suspension

Question 6

this term describes an over-reaction of the body’s immune system to a drug

Answer 6

autoimmune reaction

Question 7

these lymphocytes produce antibodies

Answer 7

B-lymphocytes

Question 8

these lymphocytes tend to be more suppressed by glucocorticoids

Answer 8

T-lymphocytes

Question 9

these lymphocytes provide humoral immunity

Answer 9

B-lymphocytes

Question 10

these lymphocytes provide cell-mediated immunity

Answer 10

T-lymphocytes

Question 11

neutrophilia

Answer 11

“increased neutrophils”

Question 12

lymphopenia

Answer 12

“decreased lymphocytes”

Question 13

monocytosis

Answer 13

“increased monocytes”

Question 14

eosinopenia

Answer 14

“decreased eosinphils”

Question 15

Corticosteroids break down proteins. The term used to describe such a breakdown of tissue is what?

Answer 15

catabolism

Question 16

Term meaning loss of hair

Answer 16

alopecia

Question 17

Conversion of amino acids into glucose by the liver

Answer 17

gluconeogenesis

Question 18

Enzyme in the cornea of the eye that is enhanced by glucocorticoids and can cause a worsening of corneal ulcer

Answer 18

collagenase enzymes

Question 19

Protrusion of the deepest membrane of the cornea due to loss of the epithelial layer and stroma over that part of the membrane from a deep corneal ulcer

Answer 19

descemetocele

Question 20

Term that means an overproduction of hormones from the adrenal cortex

Answer 20

hyperadrenocorticism

Question 21

The person’s name associated with hyperadrenocorticism

Answer 21

Cushing

Question 22

Term that means an underproduction of hormones from the adrenal cortex

Answer 22

hypoadrenocorticism

Question 23

The person’s name for which the condition of hypo adrenocorticism is named

Answer 23

Addison

Question 24

Term that means “caused by the doctor”

Answer 24

iatrogenic

Question 25

Mineralocorticoid used to treat Addison's disease signs

Answer 25

desoxycorticosterone pivalate

Question 26

Short acting glucocorticoid and a common ingredient in topical medications

Answer 26

hydrocortisone

Question 27

intermediate acting glucocorticoids; biological activity is 12-36 hours (5 drugs)

Answer 27

prednisone, prednisolone, methylprednisolone, isoflupredone, and triamcinolone

Question 28

of prednisone and prednisolone, which one must be metabolized by the liver to the active form of the drug?

Answer 28

Prednisone

Question 29

Long acting glucocorticoid drugs (2 drugs)

Answer 29

dexamethasone, betamethasone