Unit 3.6 Flashcards
Means “dry eye”
keratoconjunctivitis sicca (KCS)
Means the presence of crystals in the urine
crystalluria
What is the site of action for the following drug?
Penicillins
cell wall
What is the site of action for the following drug?
Cephalosporins
cell wall
What is the site of action for the following drug?
Aminoglycosides
ribosomal production
What is the site of action for the following drug?
Quinolones
key enzyme
What is the site of action for the following drug?
Tetracyclines
ribosomes/protein production
What is the site of action for the following drug?
Sulfonamides
intestinal tract
T or F
The “-static” antimicrobials are more dependent upon the immune system than the “-cidal” antimicrobials.
True
T or F
Time dependent antibiotics ideally need to be present at the infection site continuously.
True
T or F
Drug residues from antimicrobials typically are not degraded by cooking or pasteurization.
True
What are two compounds added to sulphonamide drugs to make them potentiated sulfas?
trimethoprim, ormetoprim
What family of antibiotics produce KCS?
sulfonamides
Besides penicillins and cephalosporins, what other antibiotic family is both filtered and actively secreted into the renal tubules resulting in high concentrations of antibiotic in the urine?
sulfonamides
Which antibiotic results in crystalluria or even damage to teh renal tubules if the concentration of drug is so high in the urine it precipitates out of solution?
sulfonamides
