UNIT 3 Flashcards

(69 cards)

1
Q

● Small, naked viruses
● Positive sense Single stranded RNA virus

A

Picornaviridae

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2
Q

Genus causing infection to man:
○ Enterovirus– enteric tract; Largest
○ Hepatovirus– liver
○ Parechovirus
○ Kobuvirus

A

Picorna

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3
Q

One of the most important because it is one of the
largest by number of members.

A

Picorna

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4
Q

has more than 280 members, so it has to be
grouped by genus.

A

Picorna

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5
Q

Causes Poliomyelitis(Polio)
● Transmission: Oral-fecal route

A

Poliovirus

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6
Q

Affects motor neurons that are myelinated

A

Poliomyelitis

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7
Q

Replicates in the oropharynx and intestinal tract

A

Polio

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8
Q

It is Irreparable once motor neurons are
damaged

A

Polio

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9
Q

Paano siya nakapunta sa spinal cord?

A

Hematogenous route

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10
Q

Oral-fecal → blood → motor neurons of
spinal cord.

A

TRUE

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11
Q

Only enterovirus with vaccine.

A

Polio

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12
Q

major disease stages of polio

A

Mild
Aseptic meningitis
Paralytic
Progressive postpoliomyelitis muscle atrophy

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13
Q

a. Sequelae of Paralytic.
b. There is still some sort of control
from the waist down(Lower
extremities).
c. Damaged motor neurons

A

Progressive Postpoliomyelitis Muscle
Atrophy

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14
Q

Would only last a few days.

A

Mild

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15
Q

BIPHASIC - First stage of fever that
would last 2-3 days, then gagaling
ka ksi no symptoms for 3-4 days
then biglang boom magkakalagnat
ka uli and mas malala na siya ksi
may kasama nang stiff neck.

A

Aseptic meningitis

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16
Q

● Second most common enterovirus

A

Coxsackie virus

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17
Q

Transmission: Oral-fecal, respiratory aerosols

A

Coxsackie virus

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18
Q

Herpangina
A16

A

Group a coxsackie virus

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19
Q

Mostly located in the mouth(Hard
and Soft Palate)

A

Herpangina

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20
Q

Most of the cases are kids or
toddlers
■ Caused by A5, A10, A16

A

A16

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21
Q

Pleurodynia or Bornholm disease
Myocarditis
Pericarditis

A

Group b

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22
Q

Has sharp stabbing pain in the
chest.
■ Treatment: Supportive

A

Pleurodynia
Bornholm

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23
Q

Leading cause of aseptic meningitis

A

Echovirus

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24
Q

Lab dx: Cell culture(Serological test not useful)

A

Echovirus

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25
_________-(Additional info) but eto tawag pag flinex yung neck tas nagjerk yung knees. ○ If positive for this, most likely it is ____
Brudzinki’s Sign meningitis
26
Infect nose and throat ● Agent of common colds ● Acid labile ● Grow better at 33°C ● Transmission: contact with contaminated hands ● More than 150 members !
human rhinovirus a,b,c
27
Can cause secondary bacterial infection
human rhinovirus a,b,c
28
acid labile
human rhinovirus
29
acid stable but can be destroyed by autoclaving and boiling
hepato a
30
Can withstand 56-60°C for 1 hour
hepato a
31
To test for this, PCR using Serum
hepato a
32
Detects total antibody
anti hav
33
Indicates recent infection(<6 months)
anti hav igm
34
Viral replication marker
HAV RNA
35
Genus: Parechovirus ● Formerly Enterovirus 22
HPeV1
36
Mainly found in saliva and the respiratory tract ○ Can cause Upper Respiratory Infection and Acute Gastroenteritis in children
HPeV1
37
Genus: Parechovirus ● Formerly Enterovirus 23
ljungan virus
38
Causes zoonotic infection (bank, vole, wild rodents
ljungan virus
39
Associated with malformations, diabetes, intrauterine deaths and sudden infant deaths in human
ljungan
40
rarely Guillain Barre Syndrome
parechovirus B 23
41
Genus: Kobuvirus ● Formerly Aichi virus
aichivirus a
42
Oyster-related
aichivirus or sapporo
43
Respiratory Enteric Orphan
sedoreo
44
Single stranded RNA virus ● First isolated in respiratory tract and enteric tract
sedoreo
45
Has 1 member: Rotavirus
sedoreo
46
Formerly Aichi virus ● Distinct wheel-shaped appearance ● Causes: upper and lower respiratory tract disease, ● gastroenteritis, diarrhea
rota a b c d f g h i j
47
Can cause infections in Villi of small intestines
rota
48
Lab dx: Stool(RNA) or ELISA
rota
49
Kids die because of dehydration.
rota
50
– commonly causes diseases in Human
rota a
51
One of the most common causes of gastroenteritis in children. ○ Only gastroenteritis with vaccine. ■ Given around 8-9 months.
rota a
52
causes diseases in other animals
a and i
53
pigs in rotavirus
H
54
birds in rota
d, f, g
55
cats
i
56
bats
j
57
Calyx – Goblet
caliciviridae
58
Slightly larger than Picornavirus
calici
59
caliciviridae Consists of 5 genera:
norovirus sapovirus nebovirus lagovirus vesivirus
60
Bovine Enteric Disease
nebovirus
61
Rabbit Hemorrhage
lagovirus
62
Affects swine, cats (feline)
vesivirus
63
Also known as Winter vomiting virus ● Transmission: Oral-fecal route, airborne ● S/S: vomiting, pagtatae as usual
norwalk virus
64
From Oysters ● Difference from Kobuvirus/Aichivirus: _____
sapporo, structure
65
Hepatitis E virus was once part of Caliciviridae and was transferred to this family
hepeviridae
66
It has high mortality and increased chances of progressing to Fulminant (full-blown) Hepatitis in pregnant patients with Hepatitis E.
hepeviridae
67
Can also cause co-infections with Hepatitis C.
hepeviridae
68
Genus: Orthohepevirus ● Causes: Hepatitis E ● Associated with Hepatitis C virus ● First isolated in 1990 ● Transmission: Oral-fecal route
orthohepevirus hepatitis e
69
Lab dx: Western blot, EM, PCR
HEPATITIS E