UNIT 3 Flashcards

1
Q

● Small, naked viruses
● Positive sense Single stranded RNA virus

A

Picornaviridae

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2
Q

Genus causing infection to man:
○ Enterovirus– enteric tract; Largest
○ Hepatovirus– liver
○ Parechovirus
○ Kobuvirus

A

Picorna

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3
Q

One of the most important because it is one of the
largest by number of members.

A

Picorna

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4
Q

has more than 280 members, so it has to be
grouped by genus.

A

Picorna

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5
Q

Causes Poliomyelitis(Polio)
● Transmission: Oral-fecal route

A

Poliovirus

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6
Q

Affects motor neurons that are myelinated

A

Poliomyelitis

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7
Q

Replicates in the oropharynx and intestinal tract

A

Polio

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8
Q

It is Irreparable once motor neurons are
damaged

A

Polio

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9
Q

Paano siya nakapunta sa spinal cord?

A

Hematogenous route

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10
Q

Oral-fecal → blood → motor neurons of
spinal cord.

A

TRUE

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11
Q

Only enterovirus with vaccine.

A

Polio

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12
Q

major disease stages of polio

A

Mild
Aseptic meningitis
Paralytic
Progressive postpoliomyelitis muscle atrophy

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13
Q

a. Sequelae of Paralytic.
b. There is still some sort of control
from the waist down(Lower
extremities).
c. Damaged motor neurons

A

Progressive Postpoliomyelitis Muscle
Atrophy

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14
Q

Would only last a few days.

A

Mild

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15
Q

BIPHASIC - First stage of fever that
would last 2-3 days, then gagaling
ka ksi no symptoms for 3-4 days
then biglang boom magkakalagnat
ka uli and mas malala na siya ksi
may kasama nang stiff neck.

A

Aseptic meningitis

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16
Q

● Second most common enterovirus

A

Coxsackie virus

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17
Q

Transmission: Oral-fecal, respiratory aerosols

A

Coxsackie virus

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18
Q

Herpangina
A16

A

Group a coxsackie virus

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19
Q

Mostly located in the mouth(Hard
and Soft Palate)

A

Herpangina

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20
Q

Most of the cases are kids or
toddlers
■ Caused by A5, A10, A16

A

A16

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21
Q

Pleurodynia or Bornholm disease
Myocarditis
Pericarditis

A

Group b

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22
Q

Has sharp stabbing pain in the
chest.
■ Treatment: Supportive

A

Pleurodynia
Bornholm

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23
Q

Leading cause of aseptic meningitis

A

Echovirus

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24
Q

Lab dx: Cell culture(Serological test not useful)

A

Echovirus

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25
Q

_________-(Additional info) but eto tawag pag
flinex yung neck tas nagjerk yung knees.
○ If positive for this, most likely it is ____

A

Brudzinki’s Sign
meningitis

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26
Q

Infect nose and throat
● Agent of common colds
● Acid labile
● Grow better at 33°C
● Transmission: contact with contaminated hands
● More than 150 members !

A

human rhinovirus a,b,c

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27
Q

Can cause secondary bacterial infection

A

human rhinovirus a,b,c

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28
Q

acid labile

A

human rhinovirus

29
Q

acid stable but can be destroyed by autoclaving and
boiling

A

hepato a

30
Q

Can withstand 56-60°C for 1 hour

A

hepato a

31
Q

To test for this, PCR using Serum

A

hepato a

32
Q

Detects total antibody

A

anti hav

33
Q

Indicates recent infection(<6 months)

A

anti hav igm

34
Q

Viral replication marker

A

HAV RNA

35
Q

Genus: Parechovirus
● Formerly Enterovirus 22

A

HPeV1

36
Q

Mainly found in saliva and the respiratory tract
○ Can cause Upper Respiratory Infection and
Acute Gastroenteritis in children

A

HPeV1

37
Q

Genus: Parechovirus
● Formerly Enterovirus 23

A

ljungan virus

38
Q

Causes zoonotic infection (bank, vole, wild rodents

A

ljungan virus

39
Q

Associated with malformations, diabetes, intrauterine
deaths and sudden infant deaths in human

A

ljungan

40
Q

rarely Guillain Barre Syndrome

A

parechovirus B 23

41
Q

Genus: Kobuvirus
● Formerly Aichi virus

A

aichivirus a

42
Q

Oyster-related

A

aichivirus or sapporo

43
Q

Respiratory Enteric Orphan

A

sedoreo

44
Q

Single stranded RNA virus
● First isolated in respiratory tract and enteric tract

A

sedoreo

45
Q

Has 1 member: Rotavirus

A

sedoreo

46
Q

Formerly Aichi virus
● Distinct wheel-shaped appearance
● Causes: upper and lower respiratory tract disease,
● gastroenteritis, diarrhea

A

rota
a
b
c
d
f
g
h
i
j

47
Q

Can cause infections in Villi of small
intestines

A

rota

48
Q

Lab dx: Stool(RNA) or ELISA

A

rota

49
Q

Kids die because of dehydration.

A

rota

50
Q

– commonly causes diseases in Human

A

rota a

51
Q

One of the most common causes of
gastroenteritis in children.
○ Only gastroenteritis with vaccine.
■ Given around 8-9 months.

A

rota a

52
Q

causes diseases in other animals

A

a and i

53
Q

pigs in rotavirus

A

H

54
Q

birds in rota

A

d, f, g

55
Q

cats

A

i

56
Q

bats

A

j

57
Q

Calyx – Goblet

A

caliciviridae

58
Q

Slightly larger than Picornavirus

A

calici

59
Q

caliciviridae Consists of 5 genera:

A

norovirus
sapovirus
nebovirus
lagovirus
vesivirus

60
Q

Bovine Enteric Disease

A

nebovirus

61
Q

Rabbit Hemorrhage

A

lagovirus

62
Q

Affects swine, cats (feline)

A

vesivirus

63
Q

Also known as Winter vomiting virus
● Transmission: Oral-fecal route, airborne
● S/S: vomiting, pagtatae as usual

A

norwalk virus

64
Q

From Oysters
● Difference from Kobuvirus/Aichivirus: _____

A

sapporo, structure

65
Q

Hepatitis E virus was once part of Caliciviridae and
was transferred to this family

A

hepeviridae

66
Q

It has high mortality and increased chances of
progressing to Fulminant (full-blown) Hepatitis in
pregnant patients with Hepatitis E.

A

hepeviridae

67
Q

Can also cause co-infections with Hepatitis C.

A

hepeviridae

68
Q

Genus: Orthohepevirus
● Causes: Hepatitis E
● Associated with Hepatitis C virus
● First isolated in 1990
● Transmission: Oral-fecal route

A

orthohepevirus
hepatitis e

69
Q

Lab dx: Western blot, EM, PCR

A

HEPATITIS E