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MYCOVIRO > DNA VIRUSES MYCOVIRO LEC > Flashcards

DNA VIRUSES MYCOVIRO LEC Flashcards

1
Q

Double stranded DNA
● With single stranded region
● Causes diseases related to liver
● can cause cancer (Hepatocarcinoma)

A

HEPADNAVIRIDAE

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2
Q

Genus: Orthohepadnavirus
● causes Hepatitis B

A

HEPATITIS B VIRUS

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3
Q

With DANE particle siya lang may ganto

A

HEPA B

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4
Q

– surface antigen –outer membrane for
screening

A

HBsAg

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5
Q

core antigen – surrounds the DNA

A

HBcAg

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6
Q

– components of the core antigen
(envelope antigens)

A

HBeAg

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7
Q

Sexual contact
● Blood transfusion
● Inoculation of contaminated secretions

A

HEPADNA

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8
Q

present in acute & chronic infection

A

HBsAg

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9
Q

indicates recovery or immunity

A

Anti-HBS

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10
Q

present in acute (<6 months) infectio

A

Anti-HBc IgM

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11
Q

previous or ongoing infection

A

Anti-HBc–

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12
Q

HBeAg– virus is replicating/ high levels
Anti-HBe– indicates lower level of HBV

A

TRUE

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13
Q

Double stranded DNA
● Causes lytic infection and latent infection
● Remain in WBC & peripheral nerves

A

HERPESVIRIDAE

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14
Q

Simplexvirus

Oral Herpes– Gingivostomatitis
HSV Encephalitis (adult)
Ocular Herpes– Keratoconjunctivitis

A

HSV 1

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15
Q

Treatment: Acyclovir

Transmission: Salivary (Oral)

A

HSV 1

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16
Q

Genital Herpes
○ Neonatal Herpes
○ HSV Encephalitis (neonates)

A

HSV 2

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17
Q

Contact with contaminated secretions
● Skin to skin contact
● Transmission between discordant partners

A

HERPES SIMPLEX 2

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18
Q

Electron Microscope
● PCR
● Pap’s Smear
● Dark Fluorescence Microscopy
● Indirect Fluorescence
● Culture

A

HERPES V 2

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19
Q

Varicellovirus

Chickenpox- auto Varicella Zoster ang tawag
Shingles (recurrent form) - Herpes Zoster

A

VZV OR HHV3

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20
Q

Droplet inhalation or respiratory droplets
● Direct contact with infectious lesions

A

VZV OR HHV3

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21
Q

Tzanck Smear
○ vesicles are used
○ multinucleated giant cells are seen in
microscopy
○ can be seen in regular microscope

A

VZV OR HHV 3

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22
Q

Genus: Lymphocryptovirus
● causes: Infectious Mononucleosis (Kissing disease)
● Produce tumors
● Associated with Burkitt’s Lymphoma and other B-cell Lymphoma

A

EBV OR HHV4

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23
Q

Hematology – differential smear

Immunology:
○ Heterophil Antibody test
○ Monospot test
○ EBV Specific Antibody test

A

EBV OR HHV 4

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24
Q

Viral capsid antigen

A

ANTI VCA

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25
Q

Early antigen
○ can persist up until 6 months

A

Anti-EA IgG

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26
Q

○ diffused
○ disappear after 6 minths

A

Anti-EA/D

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27
Q

○ restricted
○ persists up until 2 years

A

Anti-EA/R

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28
Q

EBV nuclear antigen

A

ANTI- EBNA

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29
Q

Genus: Cytomegalovirus
● Formerly “Salivary gland” virus
○ Salivary Gland Cancer

A

CMV OR HHV 5

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30
Q

Cytomegalic inclusion disease

Pneumonia (in immunosuppressed pts)

Similar to mononucleosis

Remain latent in WBC, endothelial organs

A

CMV O HHV5

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31
Q

Sexual contact
● Transplacental
● Blood transfusion

A

CMV OR HHV5

32
Q

Microscopy –
● Shell vial culture
● Serologic tests
● PCR
“Owl’s eyes” appearance

A

CMV OR HHV 5

33
Q

Genus: Roseolovirus

causes
○ Exanthem subitum or Roseola infantum or
6th disease

INFECT T CELLS

A

HHV6

34
Q

Inhalation
Respiratory droplets

PCR
Isolated thru T-cell culture

A

HHV6

35
Q

Genus: Rhadinovirus
○ common in AIDS patients

A

HHV 8

36
Q

causes
○ Kaposi sarcoma in the Thoracic Cavity

● Transmission: Sexual contact
● Diagnosis: PCR
● Cannot be recovered in cell culture

A

HHV 8

37
Q

Double stranded DNA
● Replicate in cytoplasm

A

POXVIRIDAE

38
Q

Largest and most complex of all virus
● Brick or ovoid shape
● Produces skin lesions

A

POXVIRIDAE

39
Q

Genus: Orthopoxvirus
● Causes: Smallpox
● First virus to be eradicated

Transmission: Inhalation of respiratory droplets, Saliva

A

VARIOLA OR SMALLPOX

40
Q

Genus: Orthopoxvirus
● Non-pathogenic to man
● Used in the development of smallpox vaccine

A

VACCINIA

41
Q

Genus: Molluscipoxvirus
● Cause: small pink warts (benign tumors in skin);

A

MOLLUSCUM CONTAGIOSUM VIRUS

42
Q

Transmission: Direct contact, use of contaminated
fomites
● Diagnosis: Excisional biopsy, PCR

A

MOLLUSCUM CONTAGIOSUM VIRUS

43
Q

Genus: Orthopoxvirus
● Zoonotic infection (cows)
○ when farmers milk cows, they can get this
infection
● Transmission: Touching udder of infected cow
(animal to man)

A

COWPOX

44
Q

Orthopoxvirus
● Zoonotic infection (monkeys, rodents)

Transmission: Direct inoculation, contact with
contaminated blood

Gambian rats

A

MONKEYPOX

45
Q

Diagnosis: PCR
○ Signs & Symptoms: Lymphadenopathy in the
axillary area

Treatment: supportive
○ Lesions appear in 2-3 weeks(14-21 days)
isolation period

A

MONKEYPOX

46
Q

VARIOLA OR SMALL POX
VACCINIA
COWPOX
MONKEY POX

A

ORTHOPOXVIRUS

47
Q

Genus: Parapoxvirus
● Zoonotic infection (goats, sheep)
○ occupational disease of sheep farmers
● arms, forearms, fingers

A

ORF VIRUS

48
Q

Causes: Orf or contagiosum pustular dermatitis

Transmission: Direct inoculation or contact with
contaminated equipment in broken skin

A

ORF VIRUS

49
Q

Single stranded linear DNA
● Very small naked virus
● smallest DNA virus on Earth

A

PARVOVIRIDAE

50
Q

DEFECTIVE
NON-DEFECTIVE

A

PARVOVIRIDAE

51
Q

Genus: Erythrovirus
Causes: Erythema infectiosum (5th disease)

slapped cheek appearance

● Transmission: Respiratory droplets, blood borne
● Diagnosis: PCR

A

B19

52
Q

Genus: Bocavirus

Causes: variety of upper and lower respiratory tract
illness
● common in children (wheezing sound)
● Transmission: Respiratory droplets
● Diagnosis: PCR

A

HBoV

53
Q

Double stranded DNA
● Causes warts and condylomas in man
● one of the 7 cancer viruses
● 150 serotypes
● Viral cause of tumor in man

A

PAPILLO

54
Q

Causes: Condyloma acuminate

A

HPV

55
Q

40- sexually transmitted
● Most common STD
● Transmission: Sexual contact, skin to skin
● Diagnosis: Pap’s smea

A

HPV

56
Q

PLANTAR AND WARTS

A

HPV1

57
Q

2 and 4: Skin

A

HPV 2 AND 4

58
Q

Anogenital (Anal Cancer)

A

HPV 6

59
Q

16 and 18 Genital: Cervical Cancer

A

HPV 16 and 18

60
Q

Double stranded DNA
14 species are known to infect humans
● very common and typically asymptomatic in most
human populations studied
○ also a cancer virus

A

POLYO

61
Q

Kidneys of transplant patients

First isolated in urine of immunosuppressed kidney
tissue transplant patient

A

POLYOMA V 1
BK VIRUS

62
Q

In encephalopathy
○ Can cause brain tumors

First isolated from patient with progressive multifocal encephalopathy
○ can cause brain tumours

● John Cunningham
● Causes disease in AIDS patients

A

HUMAN POLYO 2
JC VIRUS

63
Q

Isolated in the nasopharyngeal
secretions (usually in kids)

Discovered in 2007 in samples of human respiratory
secretions

Named after Karolinska Institute (site of collection)

A

HUMAN POLYO 3
KI VIRUS

64
Q

Discovered in 2007 in samples of human respiratory
secretions
● Named after Washington University
○ Isolated in nasopharyngeal secretions
○ Persist in kidney and lymphoid tissues

A

HUMAN POLYO 4
WU VIRUS

65
Q

Genus: Orthopolyomavirus
● Cause: Merkel cell cancer (a form of skin cancer)
● one of the seven human oncoviruses

A

MERKELL CELL VIRUS

66
Q

HUMAN POLYO 8

A

Trichodysplasia Spinulosa virus(8)

67
Q

HUMAN POLYO 10

A

MW VIRUS MALAWI

68
Q

HUMAN POLYO 11

A

STL VIRUS (11)- ST LOUIS

69
Q

Now Jersey virus (13)

A

HUMAN POLYO 13

70
Q

Double stranded linear DNA
● 51 serotypes
● Replicate in nucleus

A

ADENOVIRIDAE

71
Q

Genus: Mastadenovirus

● cause of common cold
● Cause: upper respiratory diseases
○ Pharyngitis
○ Conjunctivitis
○ pneumonia
● Causes cancer in animals
○ Ex. Rodents

A

ADENOVIRUS

72
Q

Single stranded DNA positive sense
● Newly discovered genus
● Anello – RING (circular genome)

A

ANELLOVIRIDAE

73
Q

Genus: Alphatorquevirus
● Reported in Japanese patient in 1997
● Extremely common even in healthy individuals
● Transmission: Blood transfusion, sexual contact,
saliva droplets
○ Hepatitis of unknown cause

A

TTV OR TORQUE TENO VIRUS

74
Q

Genus: Alphatorquevirus
● Reported in Japanese patient in 1997
● Extremely common even in healthy individuals
● Transmission: Blood transfusion, sexual contact,
saliva droplets
○ Hepatitis of unknown cause

A

TTV OR TORQUE TENO VIRUS

75
Q

SINGLE STRANDED

A

ANELLO
PARVO

MYCOVIRO (10 decks)

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