Unit 1: Glucose/Electrolyte Homeostasis Flashcards

1
Q

Role of insulin

A
  • decrease blood glucose
  • secreted by Beta cells within islets if pancreas
  • insulin circulates blood stream to target certain cells and poor glucose into cell body out of blood stream
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2
Q

Role of glucagon

A
  • Increases blood glucose
  • secreted by alpha cells
  • Glucagon travels in large amounts to the liver and stimulates production of glucose
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3
Q

Types of production of glucose that glucagon stimulates

A
  • Lipolysis: metabolizes fat for energy
  • Glycogenolysis: breaking down stored glucose called glycogen that is released as glucose
  • Gluconeogenesis: production of glucose from amino acids and fatty acids
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4
Q

Importance of blood glucose levels

A

Important for energy and brain function

  • hypoglycemia - low blood sugar levels
  • hyperglycemia- diabetes mellitus
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5
Q

Role of aldosterone

A
  • Saves sodium and water and loses potassium
  • adrenal cortex secretes this
  • increases renal reabsorption of sodium and excretion if potassium
  • low blood sodium and/or high blood potassium stimulates the adrenal cortex to secrete aldosterone
  • increases blood pressure as well
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6
Q

Role of calcitonin

A
  • released in response to high blood calcium levels
  • C cells in thyroid gland secrete calcitonin
  • acts to lower blood calcium (secretes in urine or into bones)
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7
Q

The role of parathyroid hormone

A

PTH

  • Raises blood calcium to normal
  • released when blood calcium is low
  • causes calcium in the blood to increase to norma via negative feedback
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8
Q

Type I diabetes

A
  • inability to produce insulin from beta cells
  • insulin dependent
  • mostly in younger people
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9
Q

Type II diabetes

A
  • insulin receptor failure
  • cels do not respond to insulin
  • usually in adults
  • obesity is a major contributor
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10
Q

Hypervolemia

A
  • excess fluid volume in the blood
  • can be caused by heart disease (causing increased release of aldosterone which causes water retention)
  • causes high blood pressure
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11
Q

Hypovolemia

A
  • refers to low blood volume
  • can be due to loss of blood (hemorrhage) or fluid like severe vomiting/diarrhea
  • can cause low blood pressure
  • can result in shock
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12
Q

Hypernatremia

A
  • high sodium levels in the blood
  • can be due to excessive sodium intake
  • can also be due to deficiency in antidiuretic hormone , resulting in excessive loss of water
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13
Q

Hyponatremia

A
  • refers to low sodium levels in the blood
  • can be due to decreased sodium intake or excessive water intake
  • or decreased water excretion from too much antidiuretic hormone
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14
Q

Hyperkalemia

A
  • high blood potassium levels in blood
  • can be caused by deficiency of the hormone aldosterone
  • risk of cardiac arrest
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15
Q

Hypokalemia

A
  • refers to low potassium levels in the blood

- can be caused by an excess of insulin

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16
Q

Hypercalcemia

A
  • Refers to high calcium levels in blood

- can be caused by excessive parathyroid hormones

17
Q

Hypocalcemia

A
  • refers to low calcium levels in the blood

- can be caused by decreased parathyroid hormones or insufficient vitamin D intake

18
Q

What is the standard glucose curve?

A

A series of points of reference for converting optical density readings into glucose readings

19
Q

Fasted glucose ranges

A

Normal - 110 or below
Diabetes - 126 or higher
Borderline - 110-126 mg/dl