U-World 2 Flashcards

1
Q

Iron overdose tx

A

Defoxamine (binds and allows for urinary excretion)

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2
Q

Most dialyzable toxin

A

Lithium

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3
Q

Biggest risk factor for CP

A
Premature birth (causes prenatal insults to brain development)
*Spastic most common type seen in premies*
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4
Q

Infant with failure to thrive, bilateral cataracts, jaundice, and hypoglycemia likely have? caused by?

A

Galactosemia

Caused by galactose-1-phosphate uridyl

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5
Q

Pathogenesis of NEC involves? best way to avoid?

A

Gut immaturity and exposure to bacteria from enteral feeds

Breast feeding is best way to avoid

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6
Q

Best drug for Tourettes

A

Risperidone

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7
Q

Gonococcal conjunctivitis ppx

A

Topical erythromycin

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8
Q

Neonatal conjunctivitis timing

A
  • Chemical 1st 24 hours
  • Gonococcal around 3 days
  • Chlamydial around 5-14
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9
Q

NF 1 features

A

Café-Au-Lait spots, macrocephaly, feeding problems, short stature, and learning disabilities

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10
Q

HSP presentation

A

Hematuria, abdominal pain, and purpuric rash on LE w/out thrombocytopenia

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11
Q

When do SS patients spleen’s usually infart

A

By 18-36 months of life

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12
Q

‘Onion skinning’ on bone X-ray what tumor

A

Ewing sarcoma

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13
Q

TOF murmur

A

Harsh, systolic ejection murmur over the middle to left upper sternal border

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14
Q

What is McCune-Albright syndrome

A

Precocious puberty, cafe au last spots (Pigmentation) and multiple bone defects (polyostoic fibrous dysplasia)

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15
Q

What does trachoma present with

A

Follicular conjunctivitis and pannus (neovascularization) formation in the corner
Chlamydia, also infection in nasopharynx

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16
Q

Hallmark of late Lyme disease

A

Lyme arthritis

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17
Q

When is reactive arthritis seen

A

1-4 weeks after urethritis or diarrheal infection

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18
Q

What do you suspect in subcutaneous emphysema secondary to severe coughing paroxysms

A

Pneumothorax

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19
Q

Tape test is for

A

Enterobius vermicularis

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20
Q

Prenatal US of TEF shows

A

Polyhydramnios, as affected fetus cannot swallow amniotic fluid

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21
Q

What should be suspected in newborn who chokes and coughs during first feeding

A

Esophageal atresia w/ tracheoesophageal fistula

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22
Q

Colicky ab pain and “current jelly stool”? Best test in kid?

A

Intussusception

US is first line –> air contrast enema

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23
Q

Most common cause of IVH in neonates

A

Premature and low birth weight infants

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24
Q

What can a 12 month old say

A

mama, dada, and one other word

should also be able to follow simple commands and gestures

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25
Q

Vocal ability of 3 year old

A

Around 1000 words and 75% understood by a strange

3-4 word sentences

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26
Q

Why vaginal bleeding in infants under 3 months

A

Maternal estrogens can cross placenta and enter fetal blood stream
reassurance all thats needed

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27
Q

What is herpangina

A

Coxsackie A virus in 3-10 year olds

Fever, pharyngitis, and GRAY vesicles/ulcers on posterior oropharynx

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28
Q

Hair pulling disorder

A

Trichotillomania

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29
Q

Alkalosis increases risk of what after surgery

A

Postoperative apnea

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30
Q

Acid/Base of hypertrophic pyloric stenosis

A

hypochloremic, hypokalemic, metabolic alkalosis

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31
Q

Triad of congenital rubella

A

Leukocoria (white pupillary reflex) from cataracts, PDA, and hearing loss

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32
Q

Thymus visible on CXR in what aged

A

Under 3 years

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33
Q

Two MCC causes myocarditis in kids? presentation?

A

Coxsackievirus B and adenovirus

Presentation is fever, lethargy, and signs of heart failure after a viral prodrome

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34
Q

Viral myocarditis presentation

A

Fever, lethargy, and sings of heart failure after a viral prodrome

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35
Q

Breast feeding reduces the risks of what cancers in mother

A

Breast and ovarian

36
Q

What diseases do breast feeding help prevent

A

Otitis media, gastroenteritis, respiratory infections, and UTIs

37
Q

MCC of 2nd HTN in children

A

Fibromuscular dysplasia (right renal artery more common)

38
Q

What is thought to cause gradual pyloric stenosis? Features?

A

Formula feeding until symptom onset at age 3-5 weeks

-Projectile vomiting with infant hungry after

39
Q

Adolescent who presents with a nasal obstruction, visible nasal mass, and frequent nosebleeds likely?

A

Juvenile angiofibroma

40
Q

What is Todd’s paralysis

A

Poetical paralysis that usually rapidly improves within 24 hours

41
Q

Difference b/w preseptal cellulitis and orbital cellulitis

A

Preseptal is mild infection of the eyelid anterior to orbital septum, orbital cellulitis is posterior to septum and causes all the eye trouble

42
Q

Tricuspid valve atresia characterized by

A

Left axis deviation on EKG and decreased pulmonary markings on chest X-ray

43
Q

Things seen in Edwards syndrome

A

Micrognathia, microcephaly, rocker bottom feet, overlapping fingers, and absent palmar creases
VSD common

44
Q

Polycythemia in neonates? Most common symptoms

A

Hit >65%

Lethargy, irritability, and jitteriness

45
Q

CF pneumonia bug to think of in those below 20? above?

A

Below - S. aureus (IV Vanc)

Above - Pseudomonas

46
Q

Osteomyelitis in SS kids

A

Salmonella

47
Q

Botulin paralysis in babies

A

Descending flaccid paralysis

48
Q

DM type 1 onset

A

4-6 or early puberty (bimodal)

UA, chemistry, A1c workup

49
Q

DOC for absence seizures

A

Ethosuxamide (best) or valproic acid

50
Q

Typical presentation of cholesteomas

A

New-onset hearing loss or chronic ear drainage despite antibiotic therapy
Can see granulation tissue and skin debris

51
Q

3 characteristic facial dysmorphisms of FAS

A
  1. Small palpebral fissures
  2. Smooth filtrum
  3. Thin vermillion border
52
Q

Most common cause of proteinuria in kids

A

Transient proteinuria- can be causes by fever, stress, volume depletion
repeat urine dipstick on two separate occasions

53
Q

Suspect what with sudden onset of anemia, thrombocytopenia, and renal failure

A

Hemolytic uremic syndrome

54
Q

Factors associated with physical/sexual abuse

A

Unexplained changes in behavior or scholastic performance, unstable family economic conditions, or caregiver history of substance abuse

55
Q

Androgen insensitivity vs Mullein agenesis

A

AS: absent uterus , cryptorchid testes (XY)
MA: Normal ovaries but absent uterus and upper vagina (XX)

56
Q

Congenital syphilis

A

rash on palms and soles, hepatosplenomegaly, jaundice, anemia, and rhinorrhea
Notched teeth seen later

57
Q

Congenital CMV

A

IGUR, hepatosplenomegaly, microcephaly, hearing loss

periventricular calcifications

58
Q

Most common cyanotic heart defect in neonatal period

A

TGA

Single S2 is buzzword

59
Q

2 drugs for kids who can’t stop wetting bed

A

1st line: desmopressin

2nd line: TCAs

60
Q

Late onset CAH manifestations

A

Signs of androgen excess around 7 years w/ cystic acne, accelerated linear growth, and advanced bone age

  • normal electrolytes*
  • LH low, don’t go up with GnRH stimulation*
61
Q

Vocabulary of 2 year old

A

Around 200 words, two word phrases, 1/2 of speech ineligible

62
Q

what should be suspected in any newborn with failure to pass meconium, within 48 hours after birth, especially in setting of down syndrome

A

Hirschsprung disease

63
Q

When does stranger anxiety develop

A

6 months

64
Q

Asymmetric inguinal folds suggestive of

A

DDH

65
Q

Sturge-Weber syndrome

A

Focal or generalized seizures, MR, and port wine stain along territory of congenital nerve
Skull X-ray shows tramline of intracranial calcifications

66
Q

Most common anemia of pre-term infants? cause?

A

Anemia of prematurity
Due to diminished epo levels, shortened RBC life span, and blood loss
relatively low retic count

67
Q

Abrupt onset of fever, sore throat, dysphagia, and drooling

A

Epiglottitis

68
Q

Treatment of mumps

A

Supportive, with application of cold compresses to the parotid area or testes

69
Q

MCC of inspiratory stridor in infants? best dx

A

Laryngomalacia, characterized by inspiratory stridor worse in supine position
Laryngoscopy is the best dx

70
Q

Laryngomalacia course

A

Usually self resolves by 18 months

71
Q

Light microscopy and SEM of minimal change disease? Tx?

A

Normal light microscopy
SEM: Diffuse effacement of foot processes
Tx is steroids

72
Q

Cause of anovulation in girls who’s period just started

A

HPA axis immaturity (insufficient gonadotropin secretion)

73
Q

Posterior vermis syndrome? form what tumor

A

Truncal dystaxia, signs of ICP

Medulloblastoma

74
Q

Preseptal vs orbital cellulitis

A

Orbital has ophthalmoplegia, pain with extra ocular movements, proptosis, vision impairment

75
Q

Most common early sign of cavernous sinus thrombosis? other signs?

A

Headache, then bi periorbital edema, fundoscopy with papilledema and dilated tortuous retinal veins

76
Q

Always try what before intubation in croup

A

racemic epinephrine trial

77
Q

What should you screen prader wili kids for

A

DM 2, sleep apnea, and gastric rupture

78
Q

First line treatment for lots of bleeding due to anovulation in young girls

A

High-dose estrogen

79
Q

MCC of sepsis in SS kids without spleen

A

Strep pneumo

80
Q

What is recommended after puberty in androgen insensitivity syndrome

A

Bilateral gonadectomy

81
Q

Rickets exam? xray?

A

Craniotabes, rachitic rosary, and gene varum

C-ray includes cupping and fraying of the metaphysics of the long bones

82
Q

LOC seen with what two kinds of seizures

A

Complex partial seizures and partial seizures with secondary generalizations

83
Q

SLE associated with false positive of what test

A

RPR

84
Q

What are night terrors

A

Occurring during non-REM sleep and are characterized by fear, crying, screaming and amnesia of the event

85
Q

Isolated premature adrenarche cause by

A

increased adrenal androgen secretion

86
Q

Why fat girls more at risk for precocious puberty

A

Increased estrogen from conversion in fat