Typical Antipsychotics Flashcards
names of typical antipsychotics
Haloperidol (vangho halos)
things with suffix -azine (star gazing) like trifluoperazine, fluphenazine, chlorpromazine, and thioridazine
high potency typical antipsychotics
haloperidol, trifluoperazine, fluphenazine
how FGAs work
block D2 receptors in the CNS
low potency typical antipsychotics
thioridazine (color theory wheel)
chlorpromazine (color pro paints)
what FGA treat
treat positive symptoms of schizophrenia (vangho’s ear is gone blocking the positive voices)
can treat acute psychosis in other conditions like bipolar (crazy guy on roof)
can treat agitation and aggression (haloperidol) (angry guy on roof)
can treat tourette syndrome (marionette)
FGA half life
long half life because highly lipophilic (long tapering flag)
FGA low potency side effects
block muscarinic receptors = dry mouth, constipation, blurry vision, urinary retention (atropine in wonderland) orthostatic hypotension (passed out farmers) block H1 histamine receptors = sedation (bees, flowers, and bed)
FGA high potency side effects
EPSEs (Extra pyramid hat on roof) including acute dystonia within minutes(guy with cocked head), akathisia within days (guy knocking over chair), parkinsonism within weeks (cog wheels)
tardive dyskinesia (guy sticking out tongue)
hyperprolactinemia (galactorrhea, amenorrhea, impotence)
NMS - neuroleptic malignant syndrome (now more spicy bucket)
torsades de pointes
lower seizure threshold
NMS
neuroleptic malignant syndrome, caused by high potency FGAs, have lead pipe rigidity (guy holding lead pipe on roof), also crazy, sweaty, and tachycardia
rhabdomyolysis (eaten chicken) elevated CK
chlorpromazine side effects
corneal deposits (corn yellow paint)
thioridazine side effects
retinal deposits (deposits on retinal palette)
