Type III Hypersensitivity Flashcards

1
Q

This form of hypersensitivity is associated with an ________ complex-mediated, as a result of both ____ and ____. These reactions can be either ___________ or _________.

A

Immune

IgM, IgG

Localized, Systemic

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2
Q

Arthus Reaction dictates that a _________ hypersensitivity reaction will occur as a result of the number of _______ _______ formed, which leads to __________ and potential tissue __________.

A

Localized

Immune complexes

Vasculitis

Necrosis

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3
Q

How do Neutrophils accumulate to tissue destruction?

A

Their degranulation, leads to excess proteases and oxidases in the extracellular environment that can damage epithelial cells

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4
Q

How do blue eyes result from Canine Adenovirus Type I?

A

Neutrophil accumulation in the cornea, along with viral-antibody complexes, as a result of corneal edema

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5
Q

How does Saccharopolyspora rectivirigula contribute to hypersensitivity pneumonitis?

A

Pores are inhaled by the animal, leading to acute, localized alveolitis, vasculitis, and exudate into the alveoli

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6
Q

Describe serum sickness.

A

As a reaction to treatment for diptheria, the antibodies administered lead to an increase in immune complexes that will deposit systemically

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7
Q

What is commonly associated with Type III Hypersensitivity reactions?

A

Glomerulonephritis

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