Type III Hypersensitivity Flashcards
This form of hypersensitivity is associated with an ________ complex-mediated, as a result of both ____ and ____. These reactions can be either ___________ or _________.
Immune
IgM, IgG
Localized, Systemic
Arthus Reaction dictates that a _________ hypersensitivity reaction will occur as a result of the number of _______ _______ formed, which leads to __________ and potential tissue __________.
Localized
Immune complexes
Vasculitis
Necrosis
How do Neutrophils accumulate to tissue destruction?
Their degranulation, leads to excess proteases and oxidases in the extracellular environment that can damage epithelial cells
How do blue eyes result from Canine Adenovirus Type I?
Neutrophil accumulation in the cornea, along with viral-antibody complexes, as a result of corneal edema
How does Saccharopolyspora rectivirigula contribute to hypersensitivity pneumonitis?
Pores are inhaled by the animal, leading to acute, localized alveolitis, vasculitis, and exudate into the alveoli
Describe serum sickness.
As a reaction to treatment for diptheria, the antibodies administered lead to an increase in immune complexes that will deposit systemically
What is commonly associated with Type III Hypersensitivity reactions?
Glomerulonephritis