type 4 hypersensitivity Flashcards
1
Q
what type of reaction is type 4 hypersensitivity
A
mediated by t lymphocytes or is cell mediated
2
Q
what happens during type 4 hypersensitivity
A
Destruction of the tissue is usually
caused by direct killing by toxins from
cytotoxic T (Tc) cells
Helper T (Th) 1 and Th 17 cells
produce cytokines that recruit
phagocytes, especially macrophages
3
Q
examples of type 4 hypersensitivity include
A
acute graft rejection; skin test for TB; contact allergic reactions (poison ivy); and some autoimmune diseases
