autoimmunity Flashcards
1
Q
breakdown of homeostasis
A
autoimmunity
2
Q
what can cause autoimmune diseases
A
exposure of a previously
sequestered antigen, the development of a new antigen, the complications of
infectious disease, the emergence of forbidden clone of lymphocytes, or the
consequence of ineffective peripheral tolerance (ex: RA(rheumatoid arthritis, SLE(systemic lupus erythematosous; type 1 diabetes)
3
Q
breakdown of tolerance during which the body’s immune system begins to
recognize self-antigens as foreign
A
autoimmunity
4
Q
what is associated with autoimmunity
A
genetic factor- familial association — run in families
