graft rejection Flashcards
1
Q
what type of reaction is a graft rejection
A
alloimmune reaction
2
Q
what is most critical for graft acceptance
A
Matching the human leukocyte antigens (HLA)–DR locus
3
Q
what is transplant rejection classified by
A
classified according to time
4
Q
what are the different classifications of transplant rejection
A
hyperacute
acute
chronic
5
Q
what is hyperacute transplant rejection
A
Immediate and rare; preexisting antibody to graft antigens
6
Q
what is acute transplant rejection
A
Cell-mediated response against unmatched HLA antigens
7
Q
what is chronic transplant rejection
A
Months or years; due to a weak cell-mediated reaction against minor HLA antigens
8
Q
what is HLA
A
human luekocyte antigen
9
Q
what is HLA antibody testing
A
checks your blood for antibodies against a cell marker called HLA
