transfusion reactions Flashcards
what are the 2 major carbohydrate antigens
A and B co-dominant
how do transfusion reactions occur
individuals have antibodies to the A and B antigens they lack
anti-A and anti-B antibody production are induced by
similar antigens on naturally
occurring bacteria in the intestinal tract.
antibodies are usually of which class
IgM (isohemagglutins)
O blood type is what type of donor
universal donor
AB blood type is what type of donor
universal recipient
transfusion reactions are commonly expressed on
erythrocytes
R-h positive expresses what antigen
expresses D antigen on the RhD protein
R-h negative does not express what antigen
does not express D antigen
what percentage and people are approximately
R-h negative
15% of northern American white individuals
what antibodies can R-h negative people make if exposed to R-h positive erythrocytes
anti-D
what is hemolytic disease of a newborn
R-h negative mother gives birth to a R-h positive infant
if a patient A neg is receives O pos blood, what reaction will be shown
lysis and clumping of RBCs
