type 2 hypersen Flashcards

1
Q

main points

A

tissue specific
antibody mediated
mainly cytotoxic

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2
Q

first step

A

escaped self reactive b cells produce igm or cd4 helps it to porudce igg

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3
Q

extrinisc antifen

A

infection/ medication like penicillin

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4
Q

intrinsic antigen

A

antigen host makes

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5
Q

process of penicillin ove reeaction

A

binds to RBC
egg/igm may bind to molecule creating an antigen antibody complex

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6
Q

mechanism 1

A

activation of complicment system
I’m/g activates compliemnt proteins which kill the rbc
c3,4a,5a attract neutrophils which degranulate and release 02 radicals which are cytotoxic causing tissue damage

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7
Q

example of i=condition

A

haemolyytic anaemia

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8
Q

mechanism 2

A

formation of MAC molecule by different compliment protwins

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9
Q

function of MAC

A

attacks cell by inserting self into membrane, cell swells and dies

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10
Q

test for haemolytic anemia

A

coombs test

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11
Q
A
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