cytokines

Question 1

where are mHC class ones found

Answer 1

on all nucleated cells

Question 2

where are mhc2 foun d

Answer 2

on antigen presenting cells; macrophages, monocytes aand dendritic cells

Question 3

paracrine

Answer 3

cytokine produced by one cell and affects ones in near vicinity

Question 4

endocrine

Answer 4

cytokine affects far away cell

Question 5

autocrine

Answer 5

cell producing cytokine is also the one responding

Question 6

what is IL-2 secreted by

Answer 6

CD4

Question 7

role of IL-2

Answer 7

helps prolif of t lymphocytes

Question 8

type 1 interferons

Answer 8

IFN-alpha and IFN-beta

Question 9

type 2 Interferons

Answer 9

IFN-gamma

Question 10

role of IFN-gamma

Answer 10

activates CD4

Question 11

role of IL-12

Answer 11

acitvates NK cells
helps CD4 differentiate into TH1

Question 12

IL-8 role

Answer 12

helps move cells towards site of inflammation

Question 13

whta produces and releases crp

Answer 13

IL-6

Question 14

what acts on liver and brain

Answer 14

IL-1, IL-6, TNF-alpha

Question 15

what does TNF-allpha cause

Answer 15

vasodilation and increased vascular permeability

Question 16

fight against parasitic infections

Answer 16

IL-4,5,,13

Question 17

function of IL-1

Answer 17

produces acute inflammation and fever

Question 18

what cell produces IL-2

Answer 18

t cells

Question 19

function of IL-4

Answer 19

class switchiong to IgG and IgE

Question 20

what produces IL-4

Answer 20

Th2 cells

Question 21

what cell secretes IL-5

Answer 21

Th2

Question 22

function of IL-6

Answer 22

Th17 maturation, fever and inflammation

Question 23

what cell produces TNF-alpha

Answer 23

macrophages

Question 24

function of iL-5

Answer 24

activates eosinophils

Question 25

what produces il-6

Answer 25

macrophages

Question 26

function of IL-8

Answer 26

chemotaxis for neutrophils

Question 27

main source of IL-9

Answer 27

macrophages

Question 28

what cell produces IL-10

Answer 28

th2

Question 29

What is the function of Interferon-gamma

Answer 29

To activate macrophages

Question 30

What cell produces interferon-gamma?

Answer 30

Th1

Question 31

what cell produces IL-1

Answer 31

macrophages

Question 32

function of IL-10

Answer 32

Anti-inflammatory cytokine which inhibits TH1 cytokine production

Question 33

What is the function of TNFalpha

Answer 33

Chemotaxis for neutrophil and induces fever