type 1 hypersen

Question 1

first exposure

Answer 1

sensitization

Question 2

pathway

Answer 2

t cells activated against antigen
immune cells pick up and migrate to lymph node

Question 3

what might the antigen presenting cell present

Answer 3

co stimulatory moolecules

Question 4

naive t cell

Answer 4

before its seen the antigen

Question 5

primed t

Answer 5

after seeing anitgen and binding to co stimulatory molecule

Question 6

th2

Answer 6

differentiated by t cell

Question 7

excited th2

Answer 7

releases il-4, 5

Question 8

action of il-4

Answer 8

switches igm to ige

Question 9

action of il-5

Answer 9

releases eosinophils whuch have granules which release substances

Question 10

what do ige attach to

Answer 10

fc recepotrs on mast cells finishing the sensitisation phase

Question 11

second exposure

Answer 11

mast cell binds to antigen and degranulates releasing mediators

Question 12

chemical mediator released

Answer 12

histamine

Question 13

action of histamine

Answer 13

binds to h1 receptors causing bronchoconstriction and vasodilation in blood vessels and increases vascular oermeability so fluid may leak out leading to swellinge

Question 14

leukotrienes

Answer 14

fascilitate communication between a group of cells