immunoglobulins Flashcards
fc region of antibodyb
only heavy chains
determines isotype
what determines idiotype
fab
where do antigens bind
fab regio
what are b cells composed of
2 heavy and 2 light chains
examples of opsonins
c3b
crp
igg/igm
least abundant
igd which works alongside igm
most abundant
egg
igg composition
2 gamma heavy, 2 light
what does igg activate
classical complement pathway
can cross placenta
igg
ige
allerguic
monomer
first to be secrted
igm
acitve shape of igm
pentamer
most effective at beginning compliemnt pathway
igm
can iga cross the placenta
no
can iga serve as an opsoni
yes
main in mucosal sites
iga
present in breats milk
iga
what is iga secreted across mucous membrane as
dimer
activation of mast cells
ige
what does sepsis trigger the release of
IL-1
Which of the following antibody-type forms pentamers, contributing to increased blood viscosity?
serum igm