Tx Reactions Flashcards

1
Q

Vitals to measure pre during and post tx

A

Pulse
Blood pressure
Temperature

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2
Q

Acute reaction timing

A

Within 24 hours

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3
Q

Delayed reaction timing

A

After 24 hours

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4
Q

Acute transfusion reactions (6)

A

Acute Hemolytic
Transfusion associated sepsis
Febrile non hemolytic
Allergic
TACO
TRALI

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5
Q

Acute hemolytic main symptoms

A

Fever, back pain, doom, DIC

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6
Q

TAS sepsis main symptoms

A

Fever (spike of 2 or more)
Bacteria culture is positive

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7
Q

Febrile non hemolytic main symptoms

A

Fever, nausea, tachycardia

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8
Q

Allergic reaction main symptoms

A

Urticaria, swelling, difficulty breathing

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9
Q

Ig that causes allergic reaction

A

IgE

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10
Q

Only reaction in which we are allowed to continue tx

A

Urticaria as only symptom

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11
Q

How to prevent allergic reactions

A

Pre treat with benadryl
Washed units

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12
Q

TACO main symptoms

A

Respiratory distress, chest tightness, vein distentions, hypertension

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13
Q

TRALI main symptoms

A

Respiratory distress, sever hypoxemia
Can have a fever too
Lack of other causes for lung injury

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14
Q

Leading cause of tx associated deaths

A

TRALI

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15
Q

What symptoms can massive transfusions cause

A

Hypothermia, tingling, tetany, light headedness, hyperkalemia

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16
Q

Delayed transfusion reactions 4

A

Delayed hemolytic
Graft v Host
Purpura
Iron overload

17
Q

What usually causes DHTR

A

Newly formed antibody
Anemnestic response

18
Q

Blood group system notorious for causing DHTR

A

Kidds

19
Q

What does a screen look like for DHTR

A

Usually negative the fist time
Positive after a few samples

20
Q

GVHD main symptoms

A

Rash, fever, diarrhea, blood stool, pain, pancytopenia

21
Q

What prevents GVHD

A

Irradiation

22
Q

Post transfusion purpura main symptoms

A

Can have fever

23
Q

What causes post transfusion purpura

A

Thrombocytopenia
Must have been previously sensitized to have platelet antigens

24
Q

Antigen that most commonly causes post t purpura

A

HPA-1a

25
Q

Iron overload treatment

A

Iron chelation
Common in people who get massive transfusions (sickle cell)