Tx Reactions Flashcards
Vitals to measure pre during and post tx
Pulse
Blood pressure
Temperature
Acute reaction timing
Within 24 hours
Delayed reaction timing
After 24 hours
Acute transfusion reactions (6)
Acute Hemolytic
Transfusion associated sepsis
Febrile non hemolytic
Allergic
TACO
TRALI
Acute hemolytic main symptoms
Fever, back pain, doom, DIC
TAS sepsis main symptoms
Fever (spike of 2 or more)
Bacteria culture is positive
Febrile non hemolytic main symptoms
Fever, nausea, tachycardia
Allergic reaction main symptoms
Urticaria, swelling, difficulty breathing
Ig that causes allergic reaction
IgE
Only reaction in which we are allowed to continue tx
Urticaria as only symptom
How to prevent allergic reactions
Pre treat with benadryl
Washed units
TACO main symptoms
Respiratory distress, chest tightness, vein distentions, hypertension
TRALI main symptoms
Respiratory distress, sever hypoxemia
Can have a fever too
Lack of other causes for lung injury
Leading cause of tx associated deaths
TRALI
What symptoms can massive transfusions cause
Hypothermia, tingling, tetany, light headedness, hyperkalemia
Delayed transfusion reactions 4
Delayed hemolytic
Graft v Host
Purpura
Iron overload
What usually causes DHTR
Newly formed antibody
Anemnestic response
Blood group system notorious for causing DHTR
Kidds
What does a screen look like for DHTR
Usually negative the fist time
Positive after a few samples
GVHD main symptoms
Rash, fever, diarrhea, blood stool, pain, pancytopenia
What prevents GVHD
Irradiation
Post transfusion purpura main symptoms
Can have fever
What causes post transfusion purpura
Thrombocytopenia
Must have been previously sensitized to have platelet antigens
Antigen that most commonly causes post t purpura
HPA-1a
Iron overload treatment
Iron chelation
Common in people who get massive transfusions (sickle cell)