Tumours of bone origin Flashcards
what are the different benign tumours of bone
simple osteoma, osteoid osteoma and osteoblastoma
what bones is simple osteoma seen in
cranial bones
describe the size of osteoid osteomas and osteoblastomas
osteoid osteoma = <2cm
osteoblastoma = larger
what group of people is osteoid osteoma usually seen in
young men
what bones are affected by osteoid osteoma
can be any bone but usually appendicular skeleton(tibia and femur)
describe how reactive bone is involved in osteoid osteoma and in osteoblastoma
osteoid osteoma = surrounded by reactive bone
osteoblastoma = no reactive bone
how does the pain felt in osteoid osteoma and osteoblatoma differ
osteoid osteoma = severe nocturnal pain, responds to aspirin/NSAIDs)
osteoblastoma = no response to aspirin
what is produced by osteosarcoma tumours
osteoid matrix or mineralised bone
what group of people does osteosarcoma usually affect
75% cases < 20y/o, men > women
what bones are affected by osteosarcoma
any bone, usually long bones and 50% around knee
what does osteosarcoma usually present as
painful mass or sudden fracture
what different sites are involved in classification of osteosarcoma
intramedullary, cortical, surface
what different subtypes are involved in the classification of osteosarcoma
osteoblastic, chondroblastic, fibroblastic, telangiectatic
describe the spread of osteosarcoma
haematogenous; lungs, bone, brain
describe the behaviour of osteosarcoma
aggressive
