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MSK Week 3 > Tumors > Flashcards

Tumors Flashcards

1
Q

who usually gets an osteois osteoma?

A

young patients

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2
Q

when does pain really get bad with osteoid osteoma?

A

at night

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3
Q

what can really help osteiod osteoma?

A

NSAIDs

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4
Q

what can exacerbate osteoid osteoma?

A

alcohol

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5
Q

are osteiod osteomas usually biopsied?

A

no

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6
Q

who usually gets osteosarcoma?

A

young…ages 5-25

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7
Q

if older person gets osteosarcoma what can it be secondary to?

A

paget disease or prior radiation

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8
Q

where does osteosarcoma occur in the bone?

A

metaphyseal

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9
Q

what is the buzz word for how osteosarcoma looks?

A

sunburst

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10
Q

what is treatment for osteosarcoma?

A

systemic chemo with surgical resection

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11
Q

when do you have pain with osteosarcoma?

A

at night and at rest

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12
Q

what is histo pattern of osteosarcoma?

A

atypical cells producing osteoid

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13
Q

what can be associated with osteosarcoma?

A

retinoblastoma

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14
Q

what age gets osteochondroma?

A

young under 20

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15
Q

what is classic presentation of osteochondroma?

A

fixed mass that is painless in child

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16
Q

where doe osteochondroma grow?

A

grows away from metaphyseal

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17
Q

is there pain with osteochondroma?

A

no, unless its tendonitis or bursitis

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18
Q

what is the genetic disorder with osteochondroma

A

AD..multiple osteochondromas

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19
Q

what does osteochondroma look like on histo?

A

looks like a growth plate

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20
Q

who gets enchodromas?

A

over 30 yrs old

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21
Q

where do enchodromas grow?

A

metaphyseal, central in bone

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22
Q

what is a common anatomic location for enchodromas?

A

hand

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23
Q

is there pain with enchodromas?

A

no

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24
Q

how are enchodromas found?

A

often on accident

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25
Q

chondrosarcomas is in what ages?

A

50 and above

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26
Q

are chondrosarcomas more concerning when distal or proximal?

A

proximal

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27
Q

how do chondrosarcomas appear on Xray

A

stippled pattern suggesting cartilage

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28
Q

how does chondrosarcomas appear on histo?

A

more cellular than enchondroma, considerable atypia

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29
Q

what is classic presentation for chondrosarcomas ?

A

older patient with enlarging hip/pelvis/shoulder mass

30
Q

what is a simple/unicameral bone cyst?

A

small single bone cyst usually found at proximal humerus or femur

31
Q

name two common locations for simple/unicameral bone cyst

A

femur/humerus

32
Q

what age gets simple/unicameral bone cyst?

A

under 20

33
Q

is there pain with simple/unicameral bone cyst?

A

nah not usually

34
Q

what is a nonossifying fibroma?

A

self limiting osseous lesion

35
Q

where do you see nonossifying fibroma in bone?

A

metaphyseal

36
Q

what age gets nonossifying fibroma?

A

under 20

37
Q

how do nonossifying fibroma appear on Xray?

A

lucent with lobulated bubbly look

38
Q

how does fibrous dysplasia appear on Xray?

A

ground glass appearance

39
Q

when does fibrous dysplasia usually present?

A

childhood

40
Q

what are the two types of fibrous dysplasia?

A

monostotic

polystotic

41
Q

what can polyostotic fibrous dysplasia be associated with?

A

Mccune Albright syndrome

42
Q

how does fibrous dysplasia appear on histo?

A

immature bony trabeculae with bland fibrous stroma (alphabet soup)

43
Q

where do giant cell tumors occur in bone?

A

epiphysis of long bones

44
Q

is giant cell tumor lucent or opaque on Xray?

A

lucent

45
Q

what do you see a lot of with giant cell tumor on histo?

A

giant cells

46
Q

if you get a lesion in epiphyses of bone..what is it?

A

giant cell tumor

47
Q

where does ewing sarcoma occur in bone?

A

diaphysis

48
Q

how does ewing sarcoma appear on xray?

A

onion skinning on Xray

49
Q

what can ewing sarcoma be associated with? so what can it be confused with?

A

fever and ESR…osteomyelitis

50
Q

how does ewing sarcoma appear on histo?

A

small round monomorphic cells

51
Q

what is typical translocation of ewing sarcoma?

A

11 and 22

52
Q

what are the two pediatric osseous malignancies?

A

osteosarcoma and ewing sarcoma

53
Q

new bony lesion in patient older than 50 think what three things?

A

metastatic disease
myeloma
lymphoma

54
Q

if it is a primary tumor in someone older than 50…what two things do we think?

A

chondrosarcoma or secondary osteosarcoma

55
Q

how does MM appear on Xray?

A

multifocal and radiolucent

56
Q

what is a common site for test questions to ask about MM?

A

skull lesions

57
Q

what are five common primary cancers that spread to bone?

A 
lung
breast
prostate
renal
thyroid
58
Q

what does myositis ossificans cause in bone?

A

tumor stimulator

59
Q

what can myositis ossificans cause to form in muscle?

A

hetertropic bone

60
Q

what is a common location for myositis ossificans?

A

quad

61
Q

how does myositis ossificans appear on Xray?

A

outer rim is opaque and inner area is lucent

62
Q

why does outer area of myositis ossificans appear more opaque?

A

because the bone matures from outside to in

63
Q

how does myositis ossificans usually present?

A

young patient with trauma to leg and a developing mass after trauma

64
Q

is myositis ossificans painful?

A

not usually

65
Q

what can paget disease contribute to?

A

tumor contributor/stimulator

66
Q

what is paget disease associated with?

A

osteosarcoma

67
Q

what other organ system is problem in paget disease?

A

endocrine

68
Q

who gets paget disease?

A

older patients more than 50yo

69
Q

is paget disease painful?

A

yes

70
Q

what can you see happen to bones in paget disease?

A

bone bowing

MSK Week 3 (10 decks)

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