Tumor Suppressor Genes Flashcards
1
Q
BRCA 1, 17q
BRCA 2, 13q
A
Breast and ovarian Ca
2
Q
p53, 17p
A
Most human cancers
Li-Fraumeni syndrome
3
Q
p16, 9p
A
Melanoma
4
Q
APC, 5q
A
Colorectal cancer
5
Q
WT1, 11p
A
Wilms tumor
6
Q
NF1, 17q
NF2, 22q
A
Neurofibromatosis 1 and 2
7
Q
DPC, 18q
A
Pancreatic cancer
8
Q
DCC, 18q
A
Colon cancer
9
Q
Rb 13q
A
Retinoblastoma
Osteosarcoma