Tumor Suppressor Genes Flashcards

1
Q

BRCA 1, 17q

BRCA 2, 13q

A

Breast and ovarian Ca

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2
Q

p53, 17p

A

Most human cancers

Li-Fraumeni syndrome

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3
Q

p16, 9p

A

Melanoma

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4
Q

APC, 5q

A

Colorectal cancer

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5
Q

WT1, 11p

A

Wilms tumor

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6
Q

NF1, 17q

NF2, 22q

A

Neurofibromatosis 1 and 2

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7
Q

DPC, 18q

A

Pancreatic cancer

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8
Q

DCC, 18q

A

Colon cancer

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9
Q

Rb 13q

A

Retinoblastoma

Osteosarcoma

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