Skin

Question 1

loss of intercellular connections b/w keratinocytes

Answer 1

Acantholysis

Question 2

Epidermal hyperplasia

Answer 2

Acanthosis

Question 3

Focal loss of epidermis

Answer 3

Erosion

Question 4

Linear pattern of melanocyte proliferation in epidermal basal layer

Answer 4

Lentigenous

Question 5

Retention of nuclei in stratum corneum

Answer 5

Parakeratosis

Question 6

Epidermal intercellular edema

Answer 6

Spongiosis

Question 7

Focal loss of epidermis including dermis and subQ

Answer 7

Ulceration

Question 8

Within or adjacent to cells

Answer 8

vacuolization

Question 9

tan to brown uniformly pigmented small (

Answer 9

Melanocytic nevus

Question 10

Flat macules to slightly raises plaques with “pebbly” surface; target-like lesions with dark raised center and irreg, flat periphery

Answer 10

Dysplastic nevus

Question 11

ABCs of melanoma

Answer 11

Assymetry
Border irregularity
Color variation

Question 12

Most impt RF in melanoma

Answer 12

Sun exposure

Question 13

Most common type of melanoma, develops in LE and back

Answer 13

Superficial spreading

Question 14

Melanoma type w/ Extension of lentigo into dermis, on sun-exposed parts

Answer 14

Lentigo maligna melanoma

Question 15

Type of melanoma with no radial phase, with poor prognosis

Answer 15

Nodular melanoma

Question 16

Melanoma type located on the palm, sole or beneath the nail, common in blacks, poor prognosis

Answer 16

Acral lentigenous melanoma

Question 17

Benign epith tumor that is coin-like, macular to raised verrucoid lesion w/ stuck-on appearance

Answer 17

Seborrheic keratoses

Question 18

Multiple lesions of seborrheic keratoses

Answer 18

Dermatosis papulosa nigra

Question 19

Sign where there is rapid inc in # of keratoses; assoc w/ gastric adenoCA

Answer 19

Lesar-Trélat sign

Question 20

Cells with hyperkeratosis, horn cysts or invagination cysts

Answer 20

Basaloid cells

Question 21

Thickened, hyperpigmented skin w/ velvet-like texture; undulation of dermal papillae

Answer 21

Acanthosis nigricans

Question 22

tan-brown, red or skin-colored lesion w/ rough, sandpaper p-like consistency; sometimes w/ cutaneous horn; w/ cytologic atypia, dyskeratosis, elastosis, parakeratosis

Answer 22

Actinic keratoses

Question 23

2nd most common tumor arising on sun-exposed areas

Answer 23

SCC

Question 24

Cells w/ atypical nuclei involving ALL levels of epidermis

Answer 24

SCC

Question 25

Symmetric cup-shaped tumir filled w/ keratin debris

Answer 25

Keratoacanthoma

Question 26

Pattern in BCC w/ cells at the periphery arranged radially w/ long acis in parallel alignment

Answer 26

Basal cell carcinoma

Question 27

Superficial dermal edema w/ sparse superficial perivenular infiltrate

Answer 27

Urticaria

Question 28

Raised scaling plaques d/t reactive acanthosis and hyperkeratosis; w/ intraepidermal vesicles

Answer 28

Acute eczematous dermatitis

Question 29

Edema seeps into the intercellular spaces of epidermis (stratum spinosum)

Answer 29

Spongiosis

Question 30

Multiform target lesions

Answer 30

Erythema multiforme

Question 31

Erythema multiforme w/ erosions and hemorrhagic crusts involving the lips and oral mucosa, BSA

Answer 31

SJS

Question 32

Involves BSA >30%, diffuse necrosis and sloughing of cutanoues and mucosal epith surfaces

Answer 32

TEN

Question 33

Seen in erythema multiforme, results from chronic inflammatory infiltrate b/w dermis and epidermis

Answer 33

Interface dermatitis

Question 34

Major mechanical barrier, source of cytokines

Answer 34

Squamous epithelial cells