Skin Flashcards
loss of intercellular connections b/w keratinocytes
Acantholysis
Epidermal hyperplasia
Acanthosis
Focal loss of epidermis
Erosion
Linear pattern of melanocyte proliferation in epidermal basal layer
Lentigenous
Retention of nuclei in stratum corneum
Parakeratosis
Epidermal intercellular edema
Spongiosis
Focal loss of epidermis including dermis and subQ
Ulceration
Within or adjacent to cells
vacuolization
tan to brown uniformly pigmented small (
Melanocytic nevus
Flat macules to slightly raises plaques with “pebbly” surface; target-like lesions with dark raised center and irreg, flat periphery
Dysplastic nevus
ABCs of melanoma
Assymetry
Border irregularity
Color variation
Most impt RF in melanoma
Sun exposure
Most common type of melanoma, develops in LE and back
Superficial spreading
Melanoma type w/ Extension of lentigo into dermis, on sun-exposed parts
Lentigo maligna melanoma
Type of melanoma with no radial phase, with poor prognosis
Nodular melanoma
Melanoma type located on the palm, sole or beneath the nail, common in blacks, poor prognosis
Acral lentigenous melanoma
Benign epith tumor that is coin-like, macular to raised verrucoid lesion w/ stuck-on appearance
Seborrheic keratoses
Multiple lesions of seborrheic keratoses
Dermatosis papulosa nigra
Sign where there is rapid inc in # of keratoses; assoc w/ gastric adenoCA
Lesar-Trélat sign
Cells with hyperkeratosis, horn cysts or invagination cysts
Basaloid cells
Thickened, hyperpigmented skin w/ velvet-like texture; undulation of dermal papillae
Acanthosis nigricans
tan-brown, red or skin-colored lesion w/ rough, sandpaper p-like consistency; sometimes w/ cutaneous horn; w/ cytologic atypia, dyskeratosis, elastosis, parakeratosis
Actinic keratoses
2nd most common tumor arising on sun-exposed areas
SCC
Cells w/ atypical nuclei involving ALL levels of epidermis
SCC
