Tissue Repair Flashcards
Examples of stable cells
Liver
Kidneys
Pancreas
Examples of permanent cells
Skeletal muscles
Cardiac muscle
Neurons
What phase in the cell cycle does the permanent cells stay?
G0
GF impt in angiogenesis
VEGF
GF impt in collagen synthesis
TGF-B
Enzymes that control cell cycle checkpoints
Cyclic dependent kinases
Most abundant CHON in the body; only CHON that undergoes final modification in the RER
Collagen
Collagen type in bone, skin, tendon
Type 1
Collagen in cartilage
Type 2
Collagen type in reticulin
Type 3
Collagen type in BM
Type 4
Genetic d/o’s involving type 1 collagen
Osteogenesis imperfecta
Genetic d/o involving Type 4 collagen
Alport syndrome
Phases of wound healing
Inflammation
Proliferation
Maturation
Hallmark of tissue repair
Granulation tissue