transplant Flashcards

1
Q

3 specific infection risks with Rituximab

A

Hep B reactivation
PML
PCP pneumonia

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2
Q

Alemtuzimab 3 specific infection risks

A

CMV
PCP pneumonia
aspergillus

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3
Q

imatinib infection risks

A

VZV
Mold infections
Hep B reactivation

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4
Q

ibrutinib infection risks

A

aspergillosis including CNS

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5
Q

risks of venetoclax

A

severe prolonged neutropenia

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6
Q

drug interaction with venetoclax

A

fluconazole, can increase dose of venetoclax and induce worsening of neutropenia

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7
Q

Neutropenic patient on FQ prophylaxis with ARDS, rash, mucositis

A

strep viridian’s

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8
Q

Neutropenic patient with sepsis on B lactam therapy

A

Stenotrophomonas or ESBL

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9
Q

Neutropenic patient with sepsis while on carbapenem

A

ESBL

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10
Q

Neutropenic patient with lung and skin lesions

A

Pseudomonas aeuroginosa or Fungi

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11
Q

neutropenic patient with skin lesions, Gram + organism

A

Corynebacterium jeikeium

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12
Q

neutropenic patient with small tender papule on skin

A

candida

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13
Q

neutropenic patients with ulcerative and necrotic lesions on skin

A

aspergillus

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14
Q

neutropenic patient with multiple erythematous lesions in different stages

A

fusarium

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15
Q

atypical presentations of fusarium

A

keratitis
onychomycosis

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16
Q

neutropenic patient with tender plaques and nodules recently received G CSF

A

sweet’s syndrome

17
Q

resolved neutropenia, post engraftment abdominal pain, increased LFTs, fever, leg/flank pain

A

hepatosplenic candidiasis
inflammatory response to fungi invaded into portal vasculature

18
Q

high risk CMV status in BMT

A

D-, R +

19
Q

presentation of toxoplasmosis in BMT

A

pneumonia, encephalitis, fever

20
Q

BOOP/COP presentation

A

progressively indolent hypoxia and cough

21
Q

etiology of COP/BOOP

A

fibrosis of terminal airways leading to airflow obstructionP

22
Q

PRES timing after HSCT

A

within first three months after HSCT

23
Q

PRES medication risks

A

calcineurin inhibitors