TB

Question 1

hepatotoxicity with TB drugs

Answer 1

INH= PZA > RIF

Question 2

peripheral neuropathy

Answer 2

INH

Question 3

retrobulbar neuritis is a side effect of what drug

Answer 3

EMB

Question 4

arthalgias seen with what TB drug

Answer 4

PZA

Question 5

What TB drug can have seizures as side effect

Answer 5

INH

Question 6

treatment of intravesicular BCG complication/infection

Answer 6

rifampin, INH and EMB

Question 7

gold standard for TB diagnosis

Answer 7

culture

Question 8

first line therapy for active TB

Answer 8

RIPE
Rif/INH/PZA/EMB x 2 months
RIF/INH x 4 months

Question 9

when to extend therapy for pulmonary TB

Answer 9

culture positive at end of therapy with cavitary disease 9 months

Question 10

duration of treatment for CNS TB

Answer 10

9-12 months

Question 11

duration of therapy for bone/joint TB

Answer 11

6-9 months

Question 12

bedaquiline side effects

Answer 12

QTC prolongation

Question 13

when to start ART if HIV and CD4 < 50

Answer 13

within 2 weeksw

Question 14

when to start ART if HIV and CD4 if 50 or higher

Answer 14

within 8 weeks

Question 15

when to start ART after TB meningitis

Answer 15

within 8 weeks

Question 16

treatment of TB-IRIS

Answer 16

NSAIDs or steroids
don’t stop TB or ART treatment

Question 17

IGRAs do not have false positives with

Answer 17

BCG vaccine administration

Question 18

Preferred LTBI treatment regimens

Answer 18

INH + Rifapentine weekly x 3 months
Rifampin daily x 4 months
INH + RIF daily x 3 months