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IDBR > Bacteria > Flashcards

Bacteria Flashcards

1
Q

what type of media does legionella grow on

A

buffered charcoal yeast extract (BCYE) agar

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2
Q

neisseria gonorrhea media

A

chocolate agar

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3
Q

h flu media

A

chocolate agar

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4
Q

bordatella pertussis media

A

Regan Lowe and Bordet-Gengou media

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5
Q

leptospirosis media

A

Fletcher’s media

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6
Q

campylobacter media

A

Campy agar in microaerophilic atmospheres,

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7
Q

francisella tularensis media

A

buffered charcoal yeast extract (BCYE) agar or chocolate agar

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8
Q

organisms that need to be handled in hood in lab for safety

A

Neisseria meningitidis, Brucella species, Francisella tularensis, Yersinia pestis, Bacillus anthracis, Burkholdheria pseudomallei and Burkholdheria mallei, cocci

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9
Q

scedosporium association

A

near drowning or drowning

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10
Q

Gram negatives that ceftaroline is active against

A

E coli
Klebsiella
H flu
M. catarrhalis

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11
Q

Which GP Anaerobes is Vanc active against-4

A

Clostridia
Propionibacteria
Peptostreptococci
Actinomyces

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12
Q

VISA mechanism

A

thickened cell wall and small vancomycin binding sites resulting in vanc trapped with reduced cellular target

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13
Q

VRE mechanism

A

replacement of D-ALA-D-ALA with D-ALA-D-Lactate termini resulting in decreased vancomycin binding affinity

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14
Q

what is the target AUC/MIC Vanc

A

400 to 600

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15
Q

Vancomycin Adverse Reactions- 3

A

Nephrotoxicity
Ototoxicity
Histamine Release Syndrome

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16
Q

Telavancin side effect

A

Nephrotoxicity

17
Q

Oritavancin side effect

A

LFT elevation, False prolongation of aPTT

18
Q

Dalbavancin side effect

A

LFT elevation

19
Q

which quinolone has activity against MRSA

A

Delafloxacin

20
Q

which antibiotics are active intracellularly

A

FQ
Tetracyclines
Linezolid
TMP-SMX
Pleuromutilins

21
Q

MOA of tidezolid/linezolid

A

binds 50s ribosome and prevents formation of initiation complex

22
Q

Adverse events of Linezolid

A

Cytopenias
Peripheral and optic neuropathy
lactic acidosis
serotonin syndrome

23
Q

clindamycin adverse effects

A

Allergic reactions
Elevated AST/ALT
Diarrhea/CDI
Reversible neutropenia, thrombocytopenia, eosinophilia
Taste disturbance

24
Q

protein encoded by meCA gene

A

PBP2a

25
Q

Active antibiotics against VRE

A

Linezolid
Daptomycin
Ampicillin if MIC <32
Unasyn

26
Q

Treatment of VRE cystitis (not pyelonephritis)

A

Nitrofurantoin
Fosfomycin

27
Q

Moxifloxacin poor penetration into

A

urine - don’t use for UTIs

28
Q
A

IDBR (23 decks)

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