transmission of nerve impulses + factors affecting conduction+ refractory period- Neuronal communication Flashcards
how can an AP only travel in one direction
-depolarisation causes sodium channels to open further up the axon= an influx of sodium ions in one direction
-previous part of axon is unresponsive as it is in repolarisation
-i.e a wave of depolarisation
all or nothing principle
-an impulse is only transmitted if the initial stimulus goes above the threshold frequency
receptor potential
-increases as strength of stimulus increases
-frequency not amplitude of waves increase
when does the refractory period occur
-After an AP, there is a period of time where both sodium and potassium ion channels are closed (during hyperpolarisation)
-axon membrane is in a period of recovery and is unresponsive
significance of refractory period
-ensures action potentials are discrete i.e dont merge
-ensures one way transmission of impulse as region behind is recovering
-as a result, ensures ‘new’ APs are generated ahead
-means there is a minimum time inbetween each AP can be generated
-length of refractory period determines frequency of APs
3 main factors affecting speed of conduction
-myelination, temp and diameter of axon
myelination affecting speed of conduction
-unmyelinated v slow as depolarisation must happens along whole of axon
-myelinated increases speed as impulse jumps from node to node, shwann cells prevent depolarisation in myelin sheath
saltatory conduction
-impulse jumps from node to node due to presence of schwann cells
diameter of axon affecting speed of conduction
-axons with larger diameter = faster conduction as less resistance
(apparently have larger SA than smaller diameters=increases rate of diffusion
temp affecting speed of conduction
-colder conditions = less kinetic energy for ions so facilitated diffusion is slower= slower speed of conduction