Neurones- Neuronal communication Flashcards

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1
Q

role of neurones

A

carry electrical impulses around the body. Impulse always carried away from cell body

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2
Q

features found in all neurones

A

-axon
-cell body containing nucleus
-axon terminal at end of axon containing many nerve endings which allow neurones to connect to other neurones + receive impulses from them= network of communication

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3
Q

myelinated vs non myelinated neurones

A

-myelinated= axon insulated by a myelin sheath (formed by schwann cells) with nodes of ranvier. Electrical impulses jump from node to node= faster communication
-non myelinated= axon is uninsulated, impulse travels slower as it has to go through whole of axon

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4
Q

3 main types of neurones and role

A

sensory-carry impulses from receptors to CNS (brain or spinal cord)
relay- intermediate neurones found in CNS which connect sensory and motor neurones
motor- carry impulses from CNS to effecters e.g muscles or glands

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5
Q

features of motor neurones

A

-large cell body at one end that lies in brain or spinal cord
-nucleus always in cell body
-lots of dendrites extending from cell body, providing large SA for axon terminals of other neurones

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6
Q

features of relay neurones

A

-short, but highly branched dendrites and axons

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7
Q

features of sensory neurones

A

cell body that branches off in middle of cell
no dendrites (confused)

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8
Q

resting axon

A

not transmitting an impulse
inside of axon always has a negative electric potential compared to the outside

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9
Q

pd of resting axon

A

-70mV

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10
Q

2 factors for maintaining resting potentials

A

-active transport of sodium and potassium ions
-differential membrane permeability

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11
Q

active transport of sodium and potassium ions

A

-carrier proteins present in membranes of neurones which use ATP to actively transport 3 sodium ions out of axon for every 2 potassium in
-this creates a larger concentration of positive ions outside the axon= electrochemical gradient

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12
Q

differential membrane permeability

A

protein channels in membrane of neurones are less permeable to sodium ions than potassium which allows potassium to diffuse back down their concentration gradient at a faster rate than sodium ions

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13
Q

steps for an AP

A

-stimulus, depolarisation, repolarisation, hyperpolarisation + return to resting potential

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14
Q

stimulus (AP)

A

-stimulus triggers sodium ion channels to open allowing them to diffuse into the neurone down an electrochemical gradient
-when a large enough stimulus is detected, the RP is converted to an AP
-threshold voltage for AP to be stimulated = -55mV

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15
Q

depolarisation

A

-threshold v reached
-voltage gated sodium ion channels in axon membrane open
-sodium ions flow into axon down a conc gradient
-movement of sodium ions reduces pd across membrane, inside becomes less negative (depolarisation)
-depolarisation causes more sodium channels to open = positive feedback
-AP generated will reach +30mV

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16
Q

repolarisation

A

-1ms after pd has reached +30mV, all sodium channels close
-potassium voltage gated channels open, allowing diffusion of potassium out of the axon, down their conc gradient
-this returns pd to normal (-70mV) =(repolaristion)= negative feedback

17
Q

hyperpolarisation

A

-potassium ion channels are slow to close= too many potassium ions are outside of the axon
-pd is more negative than normal outside the axon (around -75mV)= short period of hyperpolarisation

18
Q

returning to RP

A

-once potassium voltage gated channels close, the sodium potassium pump restores the resting potantial