Translocations Flashcards

1
Q

t(8:14)

A
  • Burkitts Lymphoma
  • C-myc gene
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2
Q

t(9:22)

A
  • CML
  • BCR-ABL tyrosine kinase gene mutation
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3
Q

t(11:14)

A
  • Mantle cell Lymphoma
  • Cyclin D1 gene
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4
Q

t(14:18)

A
  • Follicular Lymphoma
  • BCL-2 gene mutation
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5
Q

t(15:17)

A
  • APL (M3 type AML)
  • Responds to All trans retinoic acid (Vit-A)
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