Translocations Flashcards
1
Q
t (8:14)
A
- Burkitts Lymphoma
- C-myc gene
2
Q
t (9:22)
A
- CML
- BCR-ABL tyrosine kinase gene mutation
3
Q
t (11:14)
A
- Mantle cell Lymphoma
- Cyclin D1 gene
4
Q
t (14:18)
A
- Follicular Lymphoma
- BCL-2 gene mutation
5
Q
t (15:17)
A
- APL (M3 type AML)
- Responds to All trans retinoic acid (Vit-A)
6
Q
t (11:22)
A
Ewings Sarcoma
Translocation of protien EWS FLI-1
Onion skin bone appearence on X-ray
