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Onc boards > Translocations > Flashcards

Translocations Flashcards

1
Q

t(15;17)

A

APML

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2
Q

t(9;22)

A

CML
Philadelphia chromosome
BCR-ABL

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3
Q

t(8;14)

A

Burkitt’s lymphoma
C-myc activation

Also t(2;8) and t(8;22)

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4
Q

t(14;18)

A

Follicular

BCL2

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5
Q

t(2;5)

A

Anaplastic large cell lymphoma, ALK+

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6
Q

t(11;14)

A

Mantel cell

Cyclin D1 overexpression

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7
Q

t(11;18) in gastric extra-nodal MZL

A

Predicts lack of response to H.pylori eradication

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8
Q

Myeloma high risk cytogenetics

A 
t(4;14)
t(14;16)
t(14;20)
del 17p
gain 1q
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Onc boards (24 decks)

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