Leukemia drugs- important AEs Flashcards
1
Q
Venetoclax
A
Tumor lysis syndrome
Metabolized by CYP3A4, need to adjust dose when given with antifungals
2
Q
Ivosidenib, enasidenib
A
Differentiation syndrome- fever, dyspnea, pulmonary infiltrates, hypoxia. Treat with steroids
3
Q
Gemtuzumab ozogamicin
A
Hepatotoxicity, including VOD
4
Q
High dose cytarabine
A
Cerebellar toxicity
Chemical conjunctivitis
