Non-melanoma skin cancers Flashcards
1
Q
SCC risk factors
A
Precursor lesions- solar keratosis, keratoacanthoma HPV Smoking Chronic wounds UV exposure Immunosuppression
2
Q
Basal cell risk factors
A
UV exposure
Male
Age > 50
Immunosuppression
3
Q
Merkel cell risk factors
A
UV exposure
Male
Age > 70
Immunosuppression
4
Q
Treatment of non-melanoma skin cancers
A
Resection
Consider SLN mapping for SCC and Merkel cell
RT for positive margins
5
Q
BCC systemic therapies
A
Hedgehog inhibitors- sonidegib, vismodegib
Cemiplimab (previously treated with or ineligible for hedgehog inhibitor)
6
Q
Hedgehog inhibitor AEs
A
Muscle spasm Alopecia Weight loss Diarrhea Nausea Fatigue
7
Q
Cutaneous SCC systemic therapies
A
Cemiplimab
Pembro
8
Q
Merkel cell systemic therapies
A
Pembro
Nivo
Avelumab
