Transducer Flashcards
First step in the adaptive process involved in blah blah is???
Recognition of the stimulus
Receptor activation reaction occurs by atleast _____ mechanisms
2
Glucocorticoid-receptor complex must undergo dissociation of ___________
Heat shock protein 90
Ligand + receptor-corepressor =???
Ligand-receptor
+
Repressor
Generally, hormones affect ___________% of the genes,mRNA, or proteins in a target cell
Less than 1%
Group 2 hormones have a ____ plasma half-life
Short
G protein
Hydrophilic or phobic
Phobic
First intracellular signal identified in mammalian cells is????
cAMP
Adenyl cyclase is encoded by atleast _____ different genes
9
Cholera and ______ toxins catalyze the ADP ribosylation of G_ and G_ respectively
Pertussis
S
I
ADP ribosylation of Gi causes _________
It prevents the dissociation of Galpha1 from beta and gamma units
G protein family
__alpha
___beta
____gamma
21
5
8
NFKB
PKA
Gprotein
Heterodimeric
Heterotetrameric
Heterotrimeric
CREB is a (weak or strong?) activator of transcription
Weak
CBP is a potent transcription activator
T/F
T
Caffeine is a derivative of _______
Methylated xanthine
A Na/Ca pump has ____ capacity and ____ affinity
A Ca/proton pump has ____ capacity and ____ affinity
High; low
Low; high
Calmodulin is homologous to ______ in structure and FUNCTION
Troponin C
A number of critical metabolic enzymes are regulated by Ca
______ synthase
______ kinase
_______ carboxylase
____________ dehydrogenase
_________ dehydrogenase
Glycogen synthase
Pyruvate
Pyruvate
G3P
Pyruvate
EGF stands for???
Epidermal growth factor
Things that can activate NFKB
Pro inflammatory cytokines
Reactive oxidative species
Mitogens
Transcription regulations by NFKB is mediated by CBP
T/F
T
