Transducer Flashcards

1
Q

First step in the adaptive process involved in blah blah is???

A

Recognition of the stimulus

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2
Q

Receptor activation reaction occurs by atleast _____ mechanisms

A

2

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3
Q

Glucocorticoid-receptor complex must undergo dissociation of ___________

A

Heat shock protein 90

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4
Q

Ligand + receptor-corepressor =???

A

Ligand-receptor

+

Repressor

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5
Q

Generally, hormones affect ___________% of the genes,mRNA, or proteins in a target cell

A

Less than 1%

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6
Q

Group 2 hormones have a ____ plasma half-life

A

Short

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7
Q

G protein

Hydrophilic or phobic

A

Phobic

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8
Q

First intracellular signal identified in mammalian cells is????

A

cAMP

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9
Q

Adenyl cyclase is encoded by atleast _____ different genes

A

9

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10
Q

Cholera and ______ toxins catalyze the ADP ribosylation of G_ and G_ respectively

A

Pertussis

S

I

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11
Q

ADP ribosylation of Gi causes _________

A

It prevents the dissociation of Galpha1 from beta and gamma units

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12
Q

G protein family

__alpha

___beta

____gamma

A

21

5

8

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13
Q

NFKB

PKA

Gprotein

A

Heterodimeric

Heterotetrameric

Heterotrimeric

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14
Q

CREB is a (weak or strong?) activator of transcription

A

Weak

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15
Q

CBP is a potent transcription activator

T/F

A

T

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16
Q

Caffeine is a derivative of _______

A

Methylated xanthine

17
Q

A Na/Ca pump has ____ capacity and ____ affinity

A Ca/proton pump has ____ capacity and ____ affinity

A

High; low

Low; high

18
Q

Calmodulin is homologous to ______ in structure and FUNCTION

A

Troponin C

19
Q

A number of critical metabolic enzymes are regulated by Ca

______ synthase

______ kinase
_______ carboxylase
____________ dehydrogenase
_________ dehydrogenase

A

Glycogen synthase

Pyruvate

Pyruvate
G3P
Pyruvate

20
Q

EGF stands for???

A

Epidermal growth factor

21
Q

Things that can activate NFKB

A

Pro inflammatory cytokines

Reactive oxidative species

Mitogens

22
Q

Transcription regulations by NFKB is mediated by CBP

T/F

A

T