Transducer Flashcards
First step in the adaptive process involved in blah blah is???
Recognition of the stimulus
Receptor activation reaction occurs by atleast _____ mechanisms
2
Glucocorticoid-receptor complex must undergo dissociation of ___________
Heat shock protein 90
Ligand + receptor-corepressor =???
Ligand-receptor
+
Repressor
Generally, hormones affect ___________% of the genes,mRNA, or proteins in a target cell
Less than 1%
Group 2 hormones have a ____ plasma half-life
Short
G protein
Hydrophilic or phobic
Phobic
First intracellular signal identified in mammalian cells is????
cAMP
Adenyl cyclase is encoded by atleast _____ different genes
9
Cholera and ______ toxins catalyze the ADP ribosylation of G_ and G_ respectively
Pertussis
S
I
ADP ribosylation of Gi causes _________
It prevents the dissociation of Galpha1 from beta and gamma units
G protein family
__alpha
___beta
____gamma
21
5
8
NFKB
PKA
Gprotein
Heterodimeric
Heterotetrameric
Heterotrimeric
CREB is a (weak or strong?) activator of transcription
Weak
CBP is a potent transcription activator
T/F
T