Transcription and translation Flashcards
Transformation
The change in DNA make up after the cell takes up DNA from it’s environment.
Where are covalent bonds in DNA
Between sugars and phosphates
Where are hydrogen bonds found in DNA
Between bases, (A&T or C&G)
Watson and Crick
Discovered the double helix shape of DNA
Nucleotide
Molecule that includes sugar, phosphate group and nitrogenous base. RNA (ribose) DNA ( deoxyribose)
Nitrogenous base
What makes each nucleotide different.
DNA bases
Adenine, Thymine,Cytosine and Guanine
RNA bases
Adenine, Uracil, Cytosine and Guanine
A Gene (molecule biologists)
A section of DNA that codes for a protien
When does DNA replication occur?
During the S (synthesis) stage of Interphase.
How does DNA replicate
It goes from one double helix strand to two strands
3 steps of DNA replication
- Initiation
- Elongation
- Termination
Step 1 Initiation
Helicase, single strand binding protein, primase, primer, and DNA polymerase
Helicase
Unwinds the double helix
Single strand binding protein
Holds the two strands of DNA apart so they don’t wind back together.
Primase
Attaches to DNA to be copied and makes complementary strand of RNA
Primer
Short section of RNA made to start the replication process
Polymerase
can only lengthen existing strand of primer to form new DNA.
Step 2 Elongation
DNA polymerase, leading strand and lagging strand.
DNA polymerase
Lengthens the DNA strand in the 5’ to 3’ direction.
Leading strand
Seamlessly follows helicase down the DNA in the 5’ - 3’ direction
Lagging strand
DNA is replicated in short strans in the opposite direction of the leading strand. Also in the 5’-3’ direction
Okazaki fragments
Shorts stans of DNA on the lagging section between the RNA primers
Step 3. Termination
DNA polymerase replaces short RNA primers with DNA
Ligase connects Okazaki segments