DNA Replication Flashcards

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1
Q

DNA

A

Contains genetic material

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2
Q

Transformation

A

A change in genotype and phenotype due to assimilation of foreign DNA

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3
Q

DNA pairing

A

Adenine and guanine = purines

Thymine and cytosine = pyrimidines

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4
Q

Semi-conservative model

A

When DNA replicates there is one strand conserved from the parent DNA and the new daughter strands forms next to it.

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5
Q

Helicase

A

An enzyme that unwinds the double helix at the origin of replication

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6
Q

Replication bubble

A

The point where the DNA is split, each end are a fork in the DNA strands

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7
Q

Single strand binding protein

A

Holds the DNA strands apart so they don’t coil back up

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8
Q

Primase

A

Binds to the DNA and makes a complementary strand of RNA called primer.

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9
Q

DNA polymerase

A

Lengthens the primer RNA and builds new DNA based on the DNA template from the parent cell.

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10
Q

Topoisomerase

A

Keeps the DNA from coiling back on the double helix.

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11
Q

Elongation

A

DNA polymerase can only lengthen in one direction from 5’ to 3’ direction

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12
Q

2 strands

A

leading

lagging .

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13
Q

leading

A

Starts at helcase stran and is seamless

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14
Q

lagging

A

DNA polymerase works away fron replication fork (5’-3’ direction), makes short, okazaki fragments joined by DNA ligase.

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15
Q

Termination

A

Diferent DNA polymerases replaces RNA bases with DNA bases, then ligase connects okazaki fregmants to complete the strand.

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16
Q

Proofreading

A

DNA polymerase replacing/repairing any incorrect nucleotides.

17
Q

Telomers

A

Nucleotides placed at the end of a DNA strand to postpone erosion of the genes

18
Q

Telomerase

A

Catalyses the lengthening of telomers in germ cells to ensure essantial genes remain in gametes.