Toxins and Antidotes Flashcards by Tom Pisano

Q

Acetaminophen

A

N-acetylcysteine (replenishes Glutathione)

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Q

AChE inhibitors, Anticholinergic agents

A

Atropine followed by palidoxime

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Q

Amphetamines (basic)

A

NH4CL (acidifies urine)

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Q

Antimuscarinics, Anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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Q

Benzo’s

A

Flumazenil

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Q

B-blockers

A

Glucagon

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Q

Carbon Monoxide

A

100% O2, Hyperbaric O2

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Q

Copper, Arsenic, gold

A

Penicillamine

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Q

Cyanide

A

Amyl-Nitrite w/ Thiosulfate; Hydroxocobalamin

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Q

Digitalis

A

Anti-dig Fab fragment

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Q

Heparin

A

Protamine Sulfate (in fish sperm)

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Q

Iron

A

deFEROxamine, deFERAsirox

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Q

Lead

A

EDTA, dimercaprol, succimer, enicillamine

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Q

Mercury, arsenic gold

A

diMERCaprol (BAL), succimer

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Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

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Q

Methemoglobin

A

METHylene blue, vitamin C

Q

Opioids

A

Nalozone

Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

Q

TCAs

A

NaHCO3 (plasma alkalinization

Q

tPA, streptokinase, urokinase

A

Aminocaproic Acid

Q

Warfarin

A

Vitamin K, plasma (if active bleeding)

Q

Serotonin

A

Cyproheptadine