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FARMA 2 > Toxicología (antídotos) > Flashcards

Toxicología (antídotos) Flashcards

1
Q

Antídoto para el paracetamol

A

Acetilcisteína

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2
Q

Mecanismo de acción de la acetilcisteína

A

Restaura niveles de glutatión en hígado

(precursor)

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3
Q

Antídoto para los organofósforos

(Sx parasimpático mimético o colinérgico)

A

Atropina

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4
Q

Mecanismo de acción de la atropina

A

Antagonista competitivo de receptores muscarínicos

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5
Q

Antídoto del metanol

A

Etanol

Fomepizol: 🚫 ADH

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6
Q

Antídoto para benzodiacepinas

(clonacepam)

A

Flumazenil

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7
Q

Mecanismo de acción del flumazenil

A

Antagonista competitivo de receptores GABAa

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8
Q

Antídoto para simpaticomiméticos

Simpaticomimeticos: cocaína, tx para TDH

A

Benzodiazepinas

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9
Q

Mecanismo de acción de las benzodiacepinas

A

Modulador alostérico puro de receptores GABAa

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10
Q

Antídoto para los opioides

Opioides: fentanilo

A
  • Naloxona
  • Naltrexona
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11
Q

Mecanismo de acción de la Naloxona

A

Antagonista competitivo de recepotres opioides (μ, κ, δ)

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12
Q

Antídoto para atropina
(Sx. anticolinérgico)

A

Fisostagmina

(inhibidor del inhibidor-acetilcolinesterasa)

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13
Q

Antídoto para síntomas cardiovasculares de un sx simpáticomimético

A

Propanolol

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14
Q

Mecanismo de acción del propanolol

A

Antagonista competitivo de receptor β adrenérgico

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15
Q

Antídoto de la heparina

A

Protamina

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16
Q

Fármaco que revierte efectos del rocuronio (bloqueador neuromuscular)

A

Sugamadex (antagonista químico)

17
Q

Antídoto para salicilatos

(ácidos débiles)

A

NaHCO3 en orina (alcaliniza)

FARMA 2 (32 decks)

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