Toxicity And Overdose Treatment Flashcards
1
Q
What criteria effects treatment of paracetamol toxicity/overdose?
A
Blood levels of drug
Time
2
Q
What can be given 0-4 hr post paracetamol overdose?
A
Activated charcoal (oral)
3
Q
How does activated charcoal work?
A
Reduces uptake of drug
4
Q
What can be given 0-36 hr post paracetamol overdose?
A
N-acetylcysteine (NAC)
5
Q
If N-Acetylcysteine cannot be given in the event of a paracetamol overdose, can be given instead?
A
Methionine
6
Q
What is used to treat opiate toxicity?
A
Naloxone
7
Q
What is the action of NAC in treating paracetamol overdose?
A
Replenishes glutathione-allows safe metabolism of NAPQI
8
Q
Why is naloxone used to treat opiate toxicity?
A
It reverse opiates
