Topic 87 - Bradsot of sheep and Köves-disease of swine (GREEN)

Question 1

What is bradsot?

Answer 1

It is a common disease, escpecially in the Northern-Europe causing sudden death in sheep

Question 2

Another name for bradsot

Answer 2

Braxy disease

Question 3

Predisposing factors needed for bradsot

Answer 3

1. Driving the animals to the winter pasture
2. The animal eats frozen feed contaminated with soil

Question 4

Causative agent for bradsot

Answer 4

Clostridium septicum

Question 5

Pathogenesis of bradsot

Answer 5

1. Entrance through a wound
2. Gas gangrene is produced in the wall of stomach and duodenum

The invasive capacity of C.septicum is very poor, so it needs a place of entry, which can be made from the forzen feed damaging the epithelium of the stomach and duodenum

Question 6

Clinical signs in case of bradsot

Answer 6

The disease has a sudden onset, so very frequently we see asymptomatic before death

1. Fever
2. Depression
3. Increased hearth rate
4. Ataxia
5. Teeth grinding

Question 7

Post mortem lesions in case of bradsot

Answer 7

They are limited to the rennet and duodenum.

1. Thickened wall
2. Necrosis of the mucous membrane
3. Fluid in the abdominal and thoracic cavity

Question 8

How to diagnose bradsot

Answer 8

Can have a diagnosis with epidemiological data + clinical signs and post mortem lesions

But to have an etiological diagnosis, we can do bacterium culture, PCR and smear

Question 9

Treatment for bradsot

Answer 9

There is NO treatment !! The disease has such a fast course, that generally there is no time

Question 10

Prevention of bradsot

Answer 10

1. Main way = Prevention of predisposing factors
2. Vaccines in teory. In practice - not used

Question 11

What is Köves disease?

Answer 11

A rare occurring disease causing sudden death in swine

Question 12

Causative agent for Köves disease

Answer 12

Clostridium septicum

Question 13

Route of infection for Köves disease

Answer 13

Köves disease needs a place of entry, such as erosions or also haemorrhages in the stomach

Question 14

Name disease that can be in the background of Köves disease

Answer 14

1. Classical swine fever
2. Transmissible gastroenteritis
3. Mycotoxins
4. Oesophageal gastric ulcer

Every disease than can cause damage to the epithelium, so clostridium has a site of entry

Question 15

Clinical signs for Köves disease

Answer 15

sudden death only

Question 16

Post mortem lesions for Köves disease

Answer 16

1. Stomach wall is thickened
2. Stomach feels like rubber when touching it
3. There are gas bubbles
4. Sometimes we can see lesions in the muscles

Question 17

How to diagnose Köves disease

Answer 17

The post mortem lesions are quite distinguishable, and can give a good indicator

We can detect the agent by:
1. Staining
2. Isolation of the agent

Also important to identify the predisposing factors because the disease in the background can be very severe and infectious

Question 18

Treatment for Köves disease

Answer 18

NO treatment !!

Question 19

Prevention for Köves disease

Answer 19

1. Preventing the predisposing factors
2. Vaccines are NOT used