topic 5 lecture notes Flashcards

1
Q

generally aerobic respiration is a ___ reaction where

A

combustion

glucose is burned in oxygen to produce CO2, H2O with the release of heat

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2
Q

molecules that contain more more oxygen contain less_____ because oxygen is strongly_____

A

free energy

electronegative

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3
Q

specifically aerobic respiration is a series of reactions that release the _____ of _____ and transfer some of the released ____ to other molecules (4)

A

free energy

gluscose

ATP, NADH H2O CO2

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4
Q

oxidation

electron donor is…

A

loses electrons

electron donor is oxidized

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5
Q

the reaction between glucose and oxygen to produce co2 and water is an

A

oxidation-reduction reaction

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6
Q

redox reactions are

A

coupled the oxidation reaction and reduction reaction occur simultaneously

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7
Q

when a molecule loses a hydrogen atom, it becomes

A

oxidized

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8
Q

a good way to think cellular respiration is _____ _____ where the potential energy of glucose is not liberated suddenly, producing only ___ and ___ but slowly released with much of its energy being transferred to other molecules.

A

controlled combustion

light and heat

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9
Q

cellular respiration can be divided into three phases (3)

A
  1. glycolysis: enzyme breaks down a molecule of glucose into two molecules of pyruvate some ATP and NADH are synthesized
  2. Pyruvate oxidation and the citric acid cycle (acetyl coAwhich is formed from pyruvate oxidation enters a metabolic cycle where it is completely oxidized to co2. Some ATP and NADH synthesized
  3. Oxidative phosphorylation (ETC)
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10
Q

glycolysis

A

consist of 10 sequential enzyme catalyzed reaction that lead to the oxidation if the 6 carbon sugar glucose producing two molecules of the 3 carbon compound pyruvate the potential energy released in the oxidation powers the synthesis of both NADH and ATP.

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11
Q

in glycolysis initially,

A

two molecules of ATP are consumed as glucose and fructose 6-phos[hate becomes phosphorylated.

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12
Q

the potential energy in 2 molecules of pyruvate is less than that of

A

one molecule of glucose- no reaction is 100% efficient!

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13
Q

in glycolysis the products are: (3)

A

2 ATP

2NADH+2H+

2Pryruvate+2H2O

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14
Q

How is ATP generated (2)

A

substrate level ohosphoralation

  • transfer of phosphate group from a higher energy substrate to ADP
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15
Q

glycolysis happens in

A

the cytosol

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16
Q

Phase 2 of glycolysis=____rxn

A

couple run

17
Q

pyruvate is___into ____ in fermentation as____

A

reduced into lactic acid

NADH goes to NAD+

18
Q

how does pyruvate pass into michtondria after glycolysis? (+concentration gradient)

A

facilitated diffusion thru first membrane (protein channels) down concentration gradient

proton gradient in second membrane
Down concentration for proton but up for pyruvate

19
Q

Once pyruvate is in the ____ pyruvate loses_____(2)…..

A

matrix

a co2 (decarboxylation)

oxidized by reducing NAD+ to NADH into acetyl CoA

20
Q

oxidation of 1 pyruvate products (3)

A
  • acetyl co A
  • NADH
    CO2 release
21
Q

citric acid Krebs cycle (3)

A
  • 8 connected some coupled reactions
  • 8 enzymes
    carbons once part of glucose get oxidized
22
Q

citric acid Krebs cycle products per 1 pyruvate (4)

A
  • 3 NADH
    -1 FADH2 (I redox run creates this)
  • 1 ATP
  • 2 co2 as citrate has 6carbons and oxaloacetate has 4)
23
Q

most usable energy stored in

A

electron carrier (NADH/FADH2more)

24
Q

ETC

A
  • ## 4 protein complexes
25
Q

the protein complexes are in

A

the matrix and Intermembrance space

26
Q

every time electron pass down the chain it

A

lose free energy

27
Q

at the end of ETC what happens?

A

oxygen accepts the electrons whose energy have been stripped off already and also gains some protons to form water. Water is a waste of respiration

28
Q

explain what etc does and why ATP is made

A

as e moves down it lose free energy which cause h+ to go into the internmenbrane space of mitochondria. They can only go down by ATP synthase so when they flow down the synthase use that energy to phosphorolayte ADP to ATP