Tobacco Cessation (final review) Flashcards

1
Q

What cancers are causally linked to smoking? (10)

A
  1. oropharynx
  2. larynx
  3. esophagus
  4. trachea, bronchus, lung
  5. acute myeloid leukemia
  6. stomach
  7. pancreas
  8. kidney & ureter
  9. cervix
  10. bladder
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2
Q

What chronic illnesses are causally linked to smoking? (11)

A
  1. stroke
  2. cataracts, blindness
  3. periodontitis
  4. aortic aneurysm
  5. coronary heart disease
  6. pneumonia
  7. vascular disease
  8. respiratory effects
  9. COPD
  10. hip fractures
  11. reproductive disease
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3
Q

Smokeless tobacco effects in the mouth include: (7)

A
  1. bad breath
  2. irritated & inflamed tissue
  3. oral cancer
  4. increased risk of tooth decay
  5. painful ulcer
  6. teeth staining
  7. periodontal/gum disease
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4
Q

Approximately _____ % of Americans are diagnosed yearly with oral/pharyngeal cancer

_______ of these cases succumb to disease

A

42,000; 8000

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5
Q

____ % of oral/pharyngeal cancer cases can be attributed to tobacco use and/or heavy alcohol consumption

A

75%

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6
Q

75% of oral/pharyngeal cancer cases can be attributed to:

A

tobacco use and/or heavy alcohol consumption

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7
Q

_____% of leukoplakias are caused by tobacco use

A

70

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8
Q

List the cessation options for tobacco cessation:

A
  1. cold turkey
  2. NRTs
  3. medications
  4. behavioral therapy
  5. combination therapy
  6. hypnotherapy
  7. acupuncture
  8. yoga, meditation
  9. herbs
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9
Q

NRTs:

A

nicotine replacement therapy

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10
Q

Behavioral therapy for tobacco cessation include:

A

counselor/coaching & apps

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11
Q

What is combination therapy for tobacco cessation:

A

multiple uses of NRTs, NRTs & medications

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12
Q

Bupropion SR is also known as:

A

Zyban

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13
Q

Bupropion SR is a:

A

smoking cessation aid (prescription)

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14
Q

Give directions for dosage & usage of Zyban:

A

150 mg sustained release tablet; begin taking one week prior to quitting, double dose after three days

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15
Q

What are the advantages of the prescription Zyban?

A
  1. easy to use
  2. can be used with NRT
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16
Q

What are the adverse effects of the prescription Zyban?

A
  1. insomnia
  2. dry mouth
  3. nervousness/difficulty concentrating
  4. rash
  5. constipation
  6. seizures
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17
Q

Varenicline is also known as:

A

chantix (prescription)

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18
Q

Give directions on dosage & usage of Varenicline (chantix):

A

0.5 mg & 1.0 mg tablets
Days 1-3: take one 0.5 mg tablet in morning
Days 4-7: take 0.5 mg tablet BID
Wees 2-12: take 1.0 mg tablet BID

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19
Q

What are the advantages of the prescription Varenicline (Chantix)?

A
  1. easy to use
  2. offers new mechanism of action for patients who have failed with other agents
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20
Q

List the adverse effects of the prescription Varenicline (Chantix):

A
  1. nausea
  2. insomnia
  3. vivid dreams
  4. constipation
  5. vomiting
  6. neuropsychiatric symptoms
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21
Q

Discuss the neuropsychiatric symptoms that may be associated with the prescription Varenicline (Chantix):

A
  1. behavioral changes
  2. aggitation
  3. depression
  4. suicidal ideation or behavior
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22
Q

Nicotine replacement therapy options include:

A
  1. gum
  2. lozenges
  3. transdermal patch
  4. nasal spray
  5. oral inhaler
23
Q

Nicorette & Zonnic are examples of what type of NRT?

A

Gum

24
Q

What are the two dosage options for Nicorette & Zonnic?

A

2mg for <25 cigs per day

4mg for 25+ cigs per day

25
Q

What are the directions for Nicorette & Zonnic? (2mg or 4mg options= same directions)

A

Week 1-6: 1 piece every 1-2 hours
Week 7-9: 1 piece every 2-4 hours
Week 10-12: 1 piece every 4-8 hours

26
Q

What is the maximum amount of Nicorette & Zonnic per day?

A

24 pieces per day

27
Q

What is an important directio to tell patients when discussing Nicorette or Zonnic?

A

No food or beverage 15 min before or during use

28
Q

The advantages & disadvantages of Nicorette & Zonnic include:

A

Advantages:
1. may delay weight gain
2. may satisfy oral cravings

Disadvantages:
1. mouth/jaw soreness
2. hiccups
3. dyspepsia

29
Q

Zonnic may be:

A

gum or lozenge

30
Q

Commit & Zonnic are examples of what type of NRT?

A

Lozenge

31
Q

What is the dosage options for Commit & Zonnic lozenges?

A

2 mg for patients who smoke after 30 min of waking

4 mg for patients who smoke within 30 min of waking

32
Q

Give directions for the NRTs Commit & Zonnic (same directions for both dosages)

A

Week 1-6: 1 lozenge every 1-2 hours
Weeks 7-9: 1 lozenge every 2-4 hours
Weeks 10-12: 1 lozenge every 4-8 hours

33
Q

What is maximum amount of Commit & Zonnic a patient can take per day?

A

20 lozenges per day

34
Q

What is an important direction to give patients that utilize Commit or Zonnic lozenges for NRTs:

A

No food or beverage 15 min before or during use, do not chew or swallow lozenge

35
Q

List the advantages & disadvantages of use of Commit or Zonnic lozenges as NRTs:

A

Advantages:
1. may delay weight gain
2. may satisfy oral cravings

Disadvantages:
1. nausea
2. hiccups
3. cough
4. heartburn
5. headache
6. insomnia

36
Q

Nicoderm CQ is an example of what type of NRT?

A

Transdermal patch

37
Q

What are the dosage options for the NRT Nicoderm CQ?

A

-7 mg
-14 mg
- 21 mg

(all 24-hour release)

38
Q

For a patient smoking less than or equal to 10 cigs per day, what are their transdermal patch directions?

A

14mg/day for 6 weeks
7 mg/day for 2 weeks

39
Q

For a patient smoking more than 10 cigs per day, what are their transdermal patch directions?

A

21mg/day for 6 weeks
14mg/day for 2 weeks
7mg/day for 2 weeks

40
Q

List the advantages & disadvantages to the NRT transdermal patches (Nicoderm CQ):

A

Advantages:
1. Provides consistent nicotine for 24 hours
2. easy to use

Disadvantages:
1. local skin reaction
2. headache
3. insomnia
4. vivid dreams

41
Q

What are the top three most common NRTs?

A

-gum
-lozenge
-transdermal patch

42
Q

Nicotrol NS is an example of what type of NRT?

A

nasal spray

43
Q

What is the dosage of Nicotrol NS?

A

0.5 mg metered spray per 50 mcL

44
Q

Describe the dosage for Nicotrol NS:

A

1-2 doses per hour
8-40 doses per day
Maximum of 5 doses per hour

45
Q

For Nicotrol NS one dose=

A

Two sprays (one per nostril)

46
Q

List the advantages & disadvantages of Nicotrol NS:

A

Advantages:
1. patients can titrate therapy to help with withdrawal

Disadvantages:
1. Nasal/throat irritation
2. rhinitis
3. tearing
4. sneezing
5. headache
6. cough

47
Q

Nicotrol is an example of what type of NRT?

A

Oral inhaler

48
Q

Describe the dosage of Nicotrol oral inhaler:

A

10 mg cartridge- delivers 4 mg inhaled nicotine vapor

49
Q

How many cartridges per day can one use of Nicotrol oral inhaler?

A

6-16 cartridges per day

50
Q

When beginning use of Nicotrol oral inhaler, begin with:

A

1 cartridge every 1-2 hours

51
Q

The best effects with Nicotrol oral inhaler occur with:

A

continuo puffing for 20 min

52
Q

List the advantages & disadvantages of the NRT nicotrol oral inhaler:

A

Advantages:
1. Patients can titrates amount to manage withdrawal
2. mimics hand-to-mouth ritual

Disadvantages:
1. mouth/throat irritation
2. cough
3. headache
4. rhinitis
5. dyspepsia

53
Q
A