Tn-HMPAO SCANNING

Question 1

CERETEC scan (the “1 stop shop” for imaging with WBC)?

is this a bone scan?

Answer 1

nope

Question 2

affect on WBC function and affinity for bone?

Answer 2

it doesnt affect it and no affinity for bone

Question 3

PMNs are seen in?

Answer 3

acute phase

Question 4

Leukocytes are seen in?

Answer 4

chronic phase

Question 5

HMPAO is better at what phase of imaging and fizzles when?

Answer 5

acute phase imaging

chronic infections

Question 6

What are the advantages of Tc-HMPAO vs. Indium?

Answer 6

Easier preparation, lower radiation dose, rapid imaging (1-4 hrs) Less blood needed for
labeling, Better images, SAFER FOR KIDS.

Question 7

Why is Tc-HMPAO not as good in long term imaging? What should you use instead for
long term?

Answer 7

WBC tag elutes 5X’s faster of the marked cells. (use Indium for 24 hr imaging.)

Question 8

If you ran studies for 24 hrs for both Ceretec & Indium for a pt with known OM. What would the results be at the 24 hr mark?

Answer 8

Ceretec = (-) OM; Indium = (+) OM

Question 9

HMPAO is best for?

Answer 9

Acute infection

Question 10

What test should you use for musculoskeletal infection, septic arthritis or OM?

Answer 10

HMPAO

Question 11

What test should you use for Chronic infections, or distinguishing between OM & DNOAP?

Answer 11

Indium

Question 12

Combined In-WBC/Tc-sulfur colloid scans are great for detecting OM in regions with?

Answer 12

active bone marrow

Question 13

What marrow scan may be the procedure of choice for acute charcot with suspected OM?

Answer 13

Sequential 4/24h Indium

Question 14

In diagnosing OM what is your next study after initial plain film radiographs?

Answer 14

MRI (always – then move to other studies)

Question 15

this is superior to leukocyte and bone scan alone or in combination

and,

is the gold standard in diferentiating diabetic infection vs. osteoarthropathy.

Answer 15

marrow imaging