HIGH YIELD I Flashcards
this is generally due to abnormal systemic stimuli (biochemical, endocrine, electrolyte abnormalities)
MBD
T/F, silent until patient presents with fracture?
T
what are the common denominators of MBD?
systemic disorders
disturbances of bone formation or resorption
mineralization defects (trabecular variations)
what are the key orthopedic disorders?
osteoporosis rickets osteomalacia hyperparathyroidism renal osteodystrophy pagets disease osteosclerosis
this is the most common metabolic bone disease and most prevalent assoc with aging?
osteoporosis
how does osteoporosis present on the plain film (percent loss)?
qualitative, 30-50% loss of bone mass requisite to demonstrate effects on cancellous bone
what are the patterns of involvement due to osteoporosis?
generalized -primary (idiopathic) --post menopausal --age-related or senile -secondary (many causes) --endocrine --congenital --nutritional --drug related regional -disuse, RSD -transient regional -inflammatory arthritis localized -tumors, infection
what kind of scan do we use for osteoporosis?
bone densitometry
- dual-energy x ray absorptiometry (DXA)
- quantitative CT (QCT)
peripheral bone mass assays
sahara clinical bone sonometer
osteopenia equals osteoporosis, T/F?
true
what are the disorders assoc with osteoporosis?
anorexia nervosa malabsorption syndrome primary hyperparathyroidism post transplantation chronic renal failure prolonged immobilization hyperthyroidism cushing's syndrome
radiographic features of osteoporosis?
decreased bone density accentuation cortical thinning insufficiency fractures reinforcement lines
significance of trabecular bone like surface area and metabolic rate?
8x surface area
higher metabolic rate
red>yellow, more vascular
*more sensitive to imbalances of formation and resorption and 1st to be affected by metabolic disorders
so moving into osteopenia, where is it 1st evident radiographically?
vertebrae pelvis ribs ends of long bones tarsal bones
how are plain film radiographic assessments qualitative?
they look at spongiosa in appendicular skeleton
patterns of spongy bone resorption (appendicular skeleton)
how does osteoporosis affect the body regionally?
disuse
transient regional
inflammatory arthritis